New month, new HOT articles! We are pleased to share a selection of our referee-recommended HOT articles in 2021. We hope you enjoy reading these articles. , Quality Control of 6-Chloronicotinic acid, 5326-23-8, Name is 6-Chloronicotinic acid, molecular formula is C6H4ClNO2, belongs to thiazines compound. In a document, author is Abu-Hashem, Ameen A., introduce the new discover.
Design, synthesis and identification of novel substituted isothiochromene analogs as potential antiviral and cytotoxic agents
In this study, we present the synthesis of novel isothiochromenes, thiazolidonone, thiazinone, arylidines, triazoles, and pyrimidinone compounds based on the starting material 3-amino- isothiochromene-4-carbonitrile 3. The chemical structures were confirmed using spectroscopic methods and elemental analyses. These compounds were screened for their in vitro antiviral and antitumor activities. Compounds 10a-c and 22a-b showed activity against herpes simplex virus-1 (HSV-1) and human immunodeficiency virus-1 (HIV-1). Compounds 15 and 21a-b exhibited activity against various types of cancer cell lines. [GRAPHICS] .
Quality Control of 6-Chloronicotinic acid, The π-electrons of these planar compounds are free to cycle around the circular arrangements of atoms found in the aromatic moieties. This stems from the resonance found in planar ring systems, like benzene, and 5326-23-8.
Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem