Academic researchers, R&D teams, teachers, students, policy makers and the media all rely on us to share knowledge that is reliable, accurate and cutting-edge. , Application of 7689-03-4, 7689-03-4, Name is Campathecin, molecular formula is C20H16N2O4, belongs to thiazines compound. In a document, author is Rai, Vijai K., introduce the new discover.
One-pot cis-selective route to sugar-fused thiazines via a masking-unmasking strategy in basic ionic liquid
A novel sequential Knoevenagel condensation, thia-Michael, and amino/mercaptoacetylative ring transformation reaction cascade for cis-selective synthesis of sugar-fused 1,3-thiazine is reported. The expeditious one-pot multicomponent annulation was performed using masked amino acid viz. 2-phenyl-1,3-oxazol-5-one or masked mercaptoacid viz. 2-methyl-2-phenyl-1,3-oxathiolan-5-one, D-xylose/D-glucose, and N-aryldithiocarbamic acid in ionic liquid [bmim] OH. The acetophenone obtained as a by-product and [bmim] OH itself could be easily recycled for further use without loss of efficiency. The envisaged method is operationally simple, high yielding, and excellent diastereoselective in favor of the cis-isomer of fused thiazines.
Interested yet? We very much hope you enjoy reading the articles and that you will join us to present your own research about 7689-03-4. Application of 7689-03-4.
Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem