Chemistry is a science major with cience and engineering. , Application In Synthesis of 2-Chloro-10H-phenothiazine, The main research directions are chemical synthesis, preparation and modification of special coatings, and research on the structure and performance of functional materials.Introducing a new discovery about 92-39-7, Name is 2-Chloro-10H-phenothiazine, molecular formula is C12H8ClNS, belongs to thiazines compound. In a document, author is Kumar, S. R. Prem.
SYNTHESIS AND BIOLOGICAL EVALUATION OF SOME NEW OXAZINES AND THIAZINES
In an approach to hostile the growing microbial drug resistance and to advance new antimicrobial moieties having more potent effect, here we have synthesized some novel substituted heterocyclic chalcone derivatives containing oxazine and thiazine moieties. Conversion of 2, 4-dihydroxyphenyl-3-phenylpropenones into 4-(2-hydrazinyl-6-phenyl-6H-1, 3-oxazin-4-yl) benzene-1,3-diols 3(a-i) was achieved by stirring 2(a-i) with semicarbazide in ethanolic sodium hydroxide. Similarly, conversion of 2(a-i) into 4-(2-hydrazinyl-6-phenyl-6H-1, 3-thiazin-4-yl) benzene-1, 3-diols 4(a-i) was achieved by stirring 2(a-i) with thiosemicarbazide in ethanolic sodium hydroxide. All the compounds were screened for in vitro antimicrobial, anti-inflammatory, and cytotoxic activity. The newly synthesized compounds exhibited significant inhibition values compared to standard drugs.
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Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem