Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Name: 1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one, 196597-78-1, Name is 1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one, molecular formula is C11H10O2, belongs to thiazines compound. In a document, author is Jun, Hee-Goo, introduce the new discover.
Microwave-assisted Solid-phase Synthesis of N-substituted-2-aminobenzo[d][1,3] Thiazine Derivatives from a BOMBA Resin
An efficient solid-phase methodology has been developed for the synthesis of N-acyl and N-sulfonyl substituted 2-aminobenzo[d][1,3] thiazine derivatives. The key step in this methodology is the preparation of backbone amide linker-bound 2-aminobenzo[d][1,3] thiazine resin through cyclization reaction between isothiocyanates and BOMBA resin under microwave irradiation. This 2-aminobenzo[d][1,3] thiazine core skeleton resin undergoes substitution reactions with various electrophiles, such as acid halides and sulfonyl halides, to generate N-acyl and N-sulfonyl substituted 2-aminobenzo[d][1,3] thiazine resins, respectively. Finally, N-acyl and N-sulfonyl-substituted 2-aminobenzo[d][1,3] thiazine derivatives are prepared in good yields and purities by cleavage of the respective resins under trifluoroacetic acid (TFA) in dichloromethane (DCM).
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 196597-78-1. Name: 1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one.
Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem