Electric Literature of 5326-23-8, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 5326-23-8, Name is 6-Chloronicotinic acid, SMILES is O=C(O)C1=CN=C(Cl)C=C1, belongs to thiazines compound. In a article, author is Ameen, M. A., introduce new discover of the category.
A new route for the synthesis of pyrimido[2,1-b][1,3]thiazine ring system
A simple and efficient pathway to conjugate monosaccharides to thienopyrimidines via click chemistry establishing a 1,2,3-triazole linker was reported. Potential pharmaceutical interest is envisaged for the expected target products. Starting from a 2-isothiocyanate-thiophene-3-carboxylate, an allylthiourea was obtained with allylamine, cyclized and S-propargylated to give a thienopyrimidine-alkyne core. Click reaction with tetraacetyl-1-azidoglucose was successful to give the target conjugate with one sugar unit. When propargylamine was used in the first step, the expected thiourea cyclized via the alkyne moiety leading to pyrimido[2,1-b][1,3]thiazine.
Electric Literature of 5326-23-8, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 5326-23-8 is helpful to your research.
Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem