In an article, author is Kumar, Pankaj, once mentioned the application of 5326-23-8, Name is 6-Chloronicotinic acid, molecular formula is C6H4ClNO2, molecular weight is 157.55, MDL number is MFCD00006241, category is thiazines. Now introduce a scientific discovery about this category, COA of Formula: C6H4ClNO2.
SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF NOVEL OXAZOLIDINONES HAVING BENZO THIAZINE DERIVATIVES
In order to develop relatively small molecules as pharmacologically active molecules, a series of novel oxazolidinones having benzothiazine and their derivatives were synthesized and characterized by IR, H-1 NMR and Mass spectral studies. Various substituted oxazolidinone benzothiazines were prepared by simple refluxing in the presence of acetonitrile. Treatment of these oxazolidinone benzothiazine derivatives with methanesulfonyl chloride gives its sulphonate derivatives which on further treatment with sodium azide and triphenyl phosphine in acetic anhydride gave acetamide derivatives. Further the synthesized compounds were evaluated for antibacterial activity against Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and antifungal activity against Candida albicans and Aspergillus niger.
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Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem