3080-99-7, Name is 3,4-Dihydro-2H-benzo[b][1,4]thiazine, belongs to thiazines compound, name: 3,4-Dihydro-2H-benzo[b][1,4]thiazine, is a common compound. In an article, once mentioned the new application about 3080-99-7.
INHIBITORS OF CYCLIN DEPENDNT KINASE 7 (CDK7)
The present invention provides novel compounds of Formula (I) and pharmaceutically acceptable salts, solvates, hydrates, tautomers, stereoisomers, isotopically labeled derivatives, and compositions thereof. Also provided are methods and kits involving the compounds or compositions for treating or preventing proliferative diseases (e.g., cancers (e.g., leukemia, melanoma, multiple myeloma), benign neoplasms, angiogenesis, inflammatory diseases, autoinflammatory diseases, and autoimmune diseases) in a subject. Treatment of a subject with a proliferative disease using a compound or composition of the invention may inhibit the aberrant activity of cyclin-dependent kinase 7 (CDK7), and therefore, induce cellular apoptosis and/or inhibit transcription in the subject.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. name: 3,4-Dihydro-2H-benzo[b][1,4]thiazine, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 3080-99-7, in my other articles.
Reference£º
Thiazine – an overview | ScienceDirect Topics,
Thiazine | C4H5NS – PubChem