Recently I am researching about ULTRASENSITIVE DETECTION; TUMOR MICROENVIRONMENT; PROTEIN-DETECTION; RATIONAL DESIGN; NANOPARTICLES; NANOMATERIALS; CELLS; STRATEGY; SIGNALS; PROBES, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21771148, 21602186, 21521004, 81430041]; Natural Science Foundation of Fujian Province of ChinaNatural Science Foundation of Fujian Province [2018J01011]; Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities [20720170088, 20720180033]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Tang, XX; Gong, XQ; Li, A; Lin, HY; Peng, CY; Zhang, XZ; Chen, XY; Gao, JH. The CAS is 56-17-7. Through research, I have a further understanding and discovery of 2,2′-Disulfanediyldiethanamine dihydrochloride. Recommanded Product: 56-17-7
Molecular probes featuring promising capabilities including specific targeting, high signal-to-noise ratio, and in situ visualization of deep tissues are in great demand for tumor diagnosis and therapy. F-19 magnetic resonance imaging (MRI) techniques incorporating stimuli-responsive probes are anticipated to be highly beneficial for specific detection and imaging of tumors because of negligible background and deep tissue penetration. Herein, we report a cascaded multi-responsive self-assembled nanoprobe, which enables sequential redox-triggered and near-infrared (NIR) irradiation-induced F-19 MR signal activation/amplification for sensing and imaging. Specifically, we designed and synthesized a cascaded multiresponsive F-19-bearing nanoprobe based on the self-assembly of amphiphilic redox-responsive F-19-containing polymers and NIR-absorbing indocyanine green (ICG) molecules. It could realize the activation of F-19 signals in the reducing tumor microenvironment and subsequent signal amplification via the photothermal process. This stepwise two-stage activation/amplification of F-19 signals was validated by F-19 NMR and MRI both in vitro and in vivo. The multiresponsive F-19 nanoprobes capable of cascaded F-19 signal activation/amplification and photothermal effect exertion can provide accurate sensing and imaging of tumors.
Welcome to talk about 56-17-7, If you have any questions, you can contact Tang, XX; Gong, XQ; Li, A; Lin, HY; Peng, CY; Zhang, XZ; Chen, XY; Gao, JH or send Email.. Recommanded Product: 56-17-7
Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem