Day: January 21, 2022

Product Details of 56-17-7. Authors Saxena, R; Srivastav, S in ELSEVIER published article about in [Saxena, Rahul; Srivastav, Sudha] Jaypee Inst Informat Technol, Dept Biotechnol, Nanobiotechnol Lab, A-10 Sect 62, Noida 201309, UP, India in 2019.0, Cited 10.0. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7

We present a sensitive single step nanobiosensor for thyroid disease diagnosis. Nanoparticles modified screen printed carbon electrode catalyzes the formation of peptide bond between anti-TSH antibody and amino coated gold nanoparticles rendering a covalently coupled antibody. The nanobiosensor detects and quantifies the thyroid stimulating hormone in the sample by sensing the effective resistance offered by electrode. As the TSH concentration increases in serum sample, more is the immunocomplex formed and higher is the resistance offered by electrode. Gold nanoparticles functionalization with cystamine dihydrochloride facilitates a covalent bonding between surface amino group and carboxylic Fc ensuring maximizing available active antibody. This strategy ensures a much lower limit of detection in addition to improved detection range due to increased loading capacity as a result of larger effective surface area offered by gold nanoparticles. These two aspects of immunosensor fabrication resulted in limit of detection as low as 0.001 mu IU/mL and an enhanced detection range of 0.001-150 mu IU/mL. This makes the developed immunosensor suitable for diagnostic purpose covering the clinically relevant range and a simple detection technique makes it potential candidate for fabrication of a Point-of-Care device for detection of Thyroid dysfunctioning. (C) 2019 Elsevier Ltd. All rights reserved.

Product Details of 56-17-7. Welcome to talk about 56-17-7, If you have any questions, you can contact Saxena, R; Srivastav, S or send Email.

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

Quality Control of 2,2′-Disulfanediyldiethanamine dihydrochloride. Zou, H; Wu, QL; Li, QW; Wang, CY; Zhou, L; Hou, XH; Yuan, WZ in [Zou, Hui; Wu, Qiliang; Li, Qianwei; Zhou, Li; Hou, Xiao-Hua] Hefei Univ Technol, Sch Chem & Chem Engn, Dept Polymer Sci & Engn, Hefei 230009, Anhui, Peoples R China; [Zou, Hui; Wu, Qiliang; Li, Qianwei; Zhou, Li; Hou, Xiao-Hua] Hefei Univ Technol, Anhui Key Lab Adv Catalyt Mat & React Engn, Hefei 230009, Anhui, Peoples R China; [Wang, Chunyao; Yuan, Weizhong] Tongji Univ, Sch Mat Sci & Engn, Shanghai 201804, Peoples R China published Thermo- and redox-responsive dumbbell-shaped copolymers: from structure design to the LCST-UCST transition in 2020.0, Cited 64.0. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7.

A dumbbell-shaped copolymer (PDMAEMA)(4)-PCL-SS-PCL-(PDMAEMA)(4) with a lower critical solution temperature (LCST) and redox responses was first synthesized by the combination of ring opening polymerization (ROP), click chemistry and atom transfer radical polymerization (ATRP). Then a dumbbell-shaped copolymer (PDMAPS)(4)-PCL-SS-PCL-(PDMAPS)(4) with an upper critical solution temperature (UCST) and redox responses was obtained through the quaternization reaction between DMAEMA and excess 1,3-propane sultone. Both (PDMAEMA)(4)-PCL-SS-PCL-(PDMAEMA)(4) and (PDMAPS)(4)-PCL-SS-PCL-(PDMAPS)(4) were amphiphilic, and they could self-assemble into spherical micelles under certain conditions. Benefitting from the LCST-type thermoresponse of PDMAEMA and UCST-type thermoresponse of PDMAPS, both dumbbell-shaped copolymers (PDMAEMA)(4)-PCL-SS-PCL-(PDMAEMA)(4) and (PDMAPS)(4)-PCL-SS-PCL-(PDMAPS)(4) presented temperature-responsive properties. The morphology and size of their assemblies would be changed when the temperature is altered. Meanwhile, due to the redox-response of disulfide bonds, both (PDMAEMA)(4)-PCL-SS-PCL-(PDMAEMA)(4) and (PDMAPS)(4)-PCL-SS-PCL-(PDMAPS)(4) showed redox-responsive properties. When dl-dithiothreitol (DTT) was added into the systems, disulfide bonds were broken, causing the change of (PDMAEMA)(4)-PCL-SS-PCL-(PDMAEMA)(4) to PCL-(PDMAEMA)(4), while (PDMAPS)(4)-PCL-SS-PCL-(PDMAPS)(4) changed into PCL-(PDMAPS)(4). The distributions of R-h for both (PDMAEMA)(4)-PCL-SS-PCL-(PDMAEMA)(4) and (PDMAPS)(4)-PCL-SS-PCL-(PDMAPS)(4) assemblies broadened with asymmetric peaks, giving rise to curves with double peaks. After 24 h, DLS curves became symmetric with a single peak, and the R-h was about half that of the original assemblies. In the meantime, dispersed spherical micelles could be observed by TEM.

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Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

An article Dual activatable self-assembled nanotheranostics for bioimaging and photodynamic therapy WOS:000585933700012 published article about IRON-OXIDE NANOPARTICLES; MAGNETIC-RESONANCE; POLYMERIC MICELLES; ENHANCED PERMEABILITY; CONTRAST AGENTS; NANOPLATFORM; CHITOSAN; DESIGN in [Fu, Yan; Yang, Hong Yu] Jilin Inst Chem Technol, Coll Mat Sci & Engn, Jilin 132022, Jilin, Peoples R China; [Wang, Nannan] Jilin Inst Chem Technol, Coll Biol & Food Engn, Jilin 132022, Jilin, Peoples R China; [Li, Yi] Jiaxing Univ, Coll Mat & Text Engn, Jiaxing 314001, Zhejiang, Peoples R China; [Wu, Te Peng; Lee, Doo Sung] Sungkyunkwan Univ, Theranost Macromol Res Ctr, Suwon 16419, Gyeonggi Do, South Korea; [Wu, Te Peng; Lee, Doo Sung] Sungkyunkwan Univ, Sch Chem Engn, Suwon 16419, Gyeonggi Do, South Korea; [Jang, Moon-Sun; Lee, Jung Hee] Sungkyunkwan Univ, Samsung Med Ctr, Sch Med, Dept Radiol, Seoul 06351, South Korea; [Jang, Moon-Sun; Lee, Jung Hee] Samsung Biomed Res Inst, Ctr Mol & Cellular Imaging, Seoul 06351, South Korea in 2020.0, Cited 53.0. Recommanded Product: 56-17-7. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7

Multifunctional nanosystems that can transport therapeutic and diagnostic agents into tumor sites and activate their respective functions via tumor-microenvironment recognition are highly desirable for clinical applications. We fabricated pH and redox dual-activatable self-assembled nanotheranostics (named as DA-SNs) via coordination-driven self-assembly of chlorin e6 (Ce6) disulfide-linked pH sensitive polymer ligand, poly (isobutylene-alt-maleic anhydride-graft-methoxy-poly (ethyleneglycol)-graft-imidazole-graft-Cystamine-Ce6) [PIMA-mPEG-API-SS-Ce6], and gadolinium ions (Gd3+). DA-SNs exhibited uniform particle size of similar to 48 nm, excellent stability, and inherent biosafety. Negatively charged DA-SNs could prolong blood circulation time (t(1/2) = 2.91 h) and improve tumor accumulation. Moreover, DA-SNs could undergo surface charge switch from negative charge to positive one in a slightly acidic tumor extracellular environment (pH 6.8), thus enhancing cellular uptake. After entering tumor cells, fluorescence, photodynamic therapeutic activity, and T1MR contrast from DA-SNs could be activated within this intracellular environment with lowered pH and high level of GSH. Importantly, human tumors implanted in mice could be successfully visualized via distinct pH and redox dual-sensitive T1MR contrast and fluorescence imaging, indicating that DA-SNs could serve as a dual-modal MR/fluorescence imaging probe for tumor-targeting diagnosis. In addition, DA-SNs exhibited superior photodynamic therapeutic efficiency with negligible side effects. Therefore, this DA-SN shows great promise for synergistic photodynamic therapy and diagnostic imaging.

Recommanded Product: 56-17-7. Bye, fridends, I hope you can learn more about C4H14Cl2N2S2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

SDS of cas: 56-17-7. Recently I am researching about AMINO-GROUPS; POLYMER; ADHESION; IMMOBILIZATION; MEMBRANES; SEGREGATION; MICROARRAYS; POLYOLEFIN; MOLECULES, Saw an article supported by the Special Coordination Funds for Promoting Science and Technology, Creation of Innovation Centers for Advanced Interdisciplinary Research Areas (Innovative Bioproduction Kobe), MEXT, JapanMinistry of Education, Culture, Sports, Science and Technology, Japan (MEXT); JSPS KAKENHIMinistry of Education, Culture, Sports, Science and Technology, Japan (MEXT)Japan Society for the Promotion of ScienceGrants-in-Aid for Scientific Research (KAKENHI) [16H04577, 18K18976, 18H04566]. Published in NATURE PUBLISHING GROUP in NEW YORK ,Authors: Hara, M; Kitahata, S; Nishimori, K; Miyahara, K; Morita, K; Tokuda, K; Nishino, T; Maruyama, T. The CAS is 56-17-7. Through research, I have a further understanding and discovery of 2,2′-Disulfanediyldiethanamine dihydrochloride

Isotactic polypropylene (PP) is one of the most popular plastics. However, the remarkably low surface energy of PP prevents the surface functionalization of PP. We studied the surface functionalization of PP by dip-coating with a maleic anhydride-grafted chlorinated polypropylene (MPO)/methacrylate-based terpolymer mixture. A methacrylate-based terpolymer (PMFP) was synthesized, which contained perfluoroalkyl (R-f)-conjugated monomers and poly(ethylene glycol)-conjugated monomers. Tape-peeling tests revealed that MPO successfully immobilized PMFP on a PP surface, although PMFP was less adhesive to PP. X-ray photoelectron spectroscopy (XPS), contact angle, and protein adsorption measurements revealed that the R-f groups and PEG chains in PMFP were segregated to the outermost surface of the dip-coated layer. The surface segregation of these moieties produced a low-fouling surface on the PP substrate. In addition, we synthesized a terpolymer that contained R-f groups and PEG chains with carboxy groups at their termini (PMFB) and used it to dip-coat a PP substrate. The surface segregation of side chains in PMFB induced the presentation of carboxy groups at the outermost surface, which were used as reactive sites for enzyme immobilization.

SDS of cas: 56-17-7. Bye, fridends, I hope you can learn more about C4H14Cl2N2S2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

I found the field of Polymer Science very interesting. Saw the article Soft poly(N-vinylcaprolactam) nanogels surface-decorated with AuNPs. Response to temperature, light, and RF-field published in 2019.0. Name: 2,2′-Disulfanediyldiethanamine dihydrochloride, Reprint Addresses Tenhu, H (corresponding author), Univ Helsinki, Dept Chem, PB 55, FIN-00014 Helsinki, Finland.. The CAS is 56-17-7. Through research, I have a further understanding and discovery of 2,2′-Disulfanediyldiethanamine dihydrochloride

Soft poly(N-vinylcaprolactam) (PNVCL) based nanogels were prepared and surface-decorated with gold nanoparticles (AuNPs). The applicability of the hybrid nanogels (PNVCL-AuNPs) as carriers for low molar mass substances was of special interest. AuNPs protected with a mixture of 11-azidoundecanothiol and 11-mercaptoundecanoic acid were bound to propargyl functionalized PNVCL based nanogels. Acidic groups on the surfaces of AuNPs and PNVCL based nanogels stabilize the particle dispersions against precipitation above the phase transition temperature of PNVCL. Both the neat PNVCL nanogels and the PVCL-AuNPs shrink upon heating the dispersions. Even though the AuNPs are mainly located in the soft surface layer of the nanogels, the PNVCL-AuNPs respond to visible light as well as to radio-frequency (RF) irradiation by shrinking due to the AuNPs acting as nanoheaters. Interactions of linear PNVCL, PNVCL nanogels and PNVCL-AuNPs with two fluorescent probes were studied as function of increasing temperature. Once bound to the polymer the fluorescent probe may or may not be released from it, depending on its polarity and water solubility. Presence of AuNPs changed the release behavior of the water soluble charged fluorescent probe from the nanogels.

Name: 2,2′-Disulfanediyldiethanamine dihydrochloride. Welcome to talk about 56-17-7, If you have any questions, you can contact Siirila, J; Karesoja, M; Pulkkinen, P; Malho, JM; Tenhu, H or send Email.

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem