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Wu, FY; Cheng, YS; Wang, DM; Li, ML; Lu, WS; Xu, XY; Zhou, XH; Wei, XW in [Wu, Feng-Yi; Wei, Xian-Wen] Anhui Normal Univ, Coll Chem & Mat Sci, Key Lab Funct Mol Solids, Anhui Lab Mol Based Mat,Minist Educ,Anhui Key Lab, Wuhu 241000, Peoples R China; [Wu, Feng-Yi; Wang, Dong-Mei; Li, Ming-Ling; Lu, Wen-Sheng; Xu, Xiao-Yong] Chaohu Univ, Sch Chem & Mat Engn, Inst Novel Funct Mat, Hefei 238000, Peoples R China; [Cheng, Yuan-Sheng] Anhui Univ Technol, Sch Chem & Chem Engn, Inst Mat Sci & Engn, Anhui Prov Key Lab Coal Clean Convers & High Valu, Maanshan 243002, Peoples R China; [Zhou, Xiu-Hong] Anhui Agr Univ, Biotechnol Ctr, Hefei 230036, Peoples R China published Nitrogen-doped MoS2 quantum dots: Facile synthesis and application for the assay of hematin in human blood in 2020.0, Cited 51.0. SDS of cas: 56-17-7. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7.

Nitrogen-doped MoS2 quantum dots (N-MoS2 QDs) were synthesized via a facile hydrothermal approach, and exhibited high fluorescence quantum yield (QY, 14.9%), excellent photostability, biocompatibility and water solubility. A novel method with good selectivity and sensitivity was established to assay hematin using N-MoS2 QDs as a fluorescent probe based on inner filter effect (IFE). Fluorescent quenching of N-MoS2 QDs has a fine linear dependence with the concentration of hematin in the range of 0.5-15 mu mol/L and a limit of detection of 0.32 mu mol/L (S/N = 3). By the detection method, average concentration of hematin in real health human erythrocytes was measured as 22.5 +/- 3.9 mu mol/L. And, recoveries range varied from 94 to 108% through standard recovery experiment. The N-MoS2 QDs probe shows excellent photostability, low cytotoxicity and anti-interference ability for hematin assay, which may become a promising method for the test of hematin in human blood.

SDS of cas: 56-17-7. Bye, fridends, I hope you can learn more about C4H14Cl2N2S2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

 

More research is needed about 2,2′-Disulfanediyldiethanamine dihydrochloride

Welcome to talk about 56-17-7, If you have any questions, you can contact Metcalf, CA; Svenson, S; Hwang, J; Tripathi, S; Gangal, G; Kabir, S; Lazarus, D; Cole, R; Sweryda-Krawiec, B; Shum, P; Brown, D; Case, RI; van der Poll, D; Rohde, E; Harlfinger, S; Teng, CH; Eliasof, S or send Email.. Recommanded Product: 56-17-7

In 2019.0 J MED CHEM published article about POLYMERIC MICELLES; CANCER THERAPEUTICS; ANTITUMOR-ACTIVITY; NANOCARRIERS; RELEASE; NANOTECHNOLOGY; NANOMEDICINE; CHALLENGES; TRANSPORT; CRLX101 in [Metcalf, Chester A., III; Case, Roy I.; Harlfinger, Stephanie; Teng, Chi-Hse] Novartis Inst BioMed Res Inc, 181 Massachusetts Ave, Cambridge, MA 02139 USA; [Svenson, Sonke; Hwang, Jungyeon; Tripathi, Snehlata; Gangal, Geeti; Kabir, Sujan; Lazarus, Douglas; Cole, Roderic; Sweryda-Krawiec, Beata; Shum, Pochi; Brown, Donna; van der Poll, Derek; Rohde, Ellen; Eliasof, Scott] Cerulean Pharma Inc, 35 Gatehouse Dr, Waltham, MA 02451 USA in 2019.0, Cited 68.0. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7. Recommanded Product: 56-17-7

Novel nanoparticle drug conjugates (NDCs) containing diverse, clinically relevant anticancer drug payloads (docetaxel, cabazitaxel, and gemcitabine) were successfully generated and tested in drug discovery studies. The NDCs utilized structurally varied linkers that attached the drug payloads to a beta-cyclodextrin-PEG copolymer to form self-assembled nanoparticles. In vitro release studies revealed a diversity of release rates driven by linker structure activity relationships (SARs). Improved in vivo pharmacokinetics (PK) for the cabazitaxel (CBTX) NDCs with glycinate-containing (1c) and hexanoate-containing linkers (2c) were demonstrated, along with high and sustained tumor levels (>168 h of released drug in tumor tissues). This led to potent efficacy and survival in both taxane- and docetaxel-resistant in vivo anticancer mouse efficacy models. Overall, the CBTX-hexanoate NDC 2c (CRLX522), demonstrated optimal and improved in vivo PK (plasma and tumor) and efficacy profile versus those of the parent drug, and the results support the potential therapeutic use of CRLX522 as a new anticancer agent.

Welcome to talk about 56-17-7, If you have any questions, you can contact Metcalf, CA; Svenson, S; Hwang, J; Tripathi, S; Gangal, G; Kabir, S; Lazarus, D; Cole, R; Sweryda-Krawiec, B; Shum, P; Brown, D; Case, RI; van der Poll, D; Rohde, E; Harlfinger, S; Teng, CH; Eliasof, S or send Email.. Recommanded Product: 56-17-7

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

 

Interesting scientific research on 56-17-7

Welcome to talk about 56-17-7, If you have any questions, you can contact Najafi, F; Salami-Kalajahi, M; Roghani-Mamaqani, H; Kahaie-Khosrowshahi, A or send Email.. Quality Control of 2,2′-Disulfanediyldiethanamine dihydrochloride

An article Effect of grafting ratio of poly(propylene imine) dendrimer onto gold nanoparticles on the properties of colloidal hybrids, their DOX loading and release behavior and cytotoxicity WOS:000471084400059 published article about POLY(AMIDOAMINE)-FUNCTIONALIZED GRAPHENE OXIDE; JANUS NANOPARTICLES; PARTICLE-SIZE; SURFACE; REDUCTION; POLYMERIZATION; METHACRYLATE; GENERATION; MECHANISM in [Najafi, Faezeh; Salami-Kalajahi, Mehdi; Roghani-Mamaqani, Hossein] Sahand Univ Technol, Dept Polymer Engn, POB 51335-1996, Tabriz, Iran; [Najafi, Faezeh; Salami-Kalajahi, Mehdi; Roghani-Mamaqani, Hossein] Sahand Univ Technol, Inst Polymer Mat, POB 51335-1996, Tabriz, Iran; [Kahaie-Khosrowshahi, Amir] Sahand Univ Technol, Dept Chem Engn, POB 51335-1996, Tabriz, Iran in 2019.0, Cited 60.0. Quality Control of 2,2′-Disulfanediyldiethanamine dihydrochloride. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7

A facile method via grafting to approach was used to synthesize hybrid gold-dendrimer nanoparticles. To this end, gold nanoparticles (GNPs) were synthesized via Turkevich method and 5th-generation cystamine-cored poly (propylene imine) (PPI) dendrimer was synthesized by iterative Michael addition and hydrogenation reactions. To prepare hybrid nanoparticles, aqueous solution of dendrimer was poured into colloidal solution of GNPs to form gold-S interactions which resulted in hybrid gold-dendrimer nanoparticles. UV-VIS-NIR and Raman spectroscopies, dynamic light scattering (DLS), thermogravimetric analysis (TGA) and field-emission scanning electron microscopy (FE-SEM) were utilized to confirm the surface modification of GNPs by PPI dendrimer. Cytotoxicity study through MIT assay against human fibroblast (FBS) cells showed appropriate proliferation of cells in presence of hybrid nanoparticles whereas higher grafting ratio of dendrimers induced more toxicity due to existence of peripheral amine groups. Also, hybrid gold-dendrimer nanoparticles were used as DOX nano-carriers. Results showed that carriers did not release the drug at pH = 7.4 significantly while up to 92.8% of drug release was measured at pH = 5.3. Also, higher grafting ratio limited the drug release due to shielding effect of grafted dendrimers.

Welcome to talk about 56-17-7, If you have any questions, you can contact Najafi, F; Salami-Kalajahi, M; Roghani-Mamaqani, H; Kahaie-Khosrowshahi, A or send Email.. Quality Control of 2,2′-Disulfanediyldiethanamine dihydrochloride

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

 

Never Underestimate The Influence Of 2,2′-Disulfanediyldiethanamine dihydrochloride

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Kurka, DW; Niehues, M; Kudruk, S; Gerke, V; Ravoo, BJ in [Kurka, Dustin Werner; Niehues, Maximilian; Ravoo, Bart Jan] Westfalische Wilhelms Univ Munster, Inst Organ Chem, Ctr Soft Nanosci, Corrensstr 36, D-48149 Munster, Germany; [Kurka, Dustin Werner; Niehues, Maximilian; Ravoo, Bart Jan] Busso Peus Str 10, D-48149 Munster, Germany; [Kudruk, Sergej; Gerke, Volker] Westfalische Wilhelms Univ Munster, Inst Med Biochem, Ctr Mol Biol Inflammat, Von Esmarch Str 56, D-48149 Munster, Germany published Polythiolactone-Decorated Silica Particles: A Versatile Approach for Surface Functionalization, Catalysis and Encapsulation in 2021.0, Cited 98.0. Recommanded Product: 56-17-7. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7.

The surface chemistry of colloidal silica has tremendous effects on its properties and applications. Commonly the design of silica particles is based on their de novo synthesis followed by surface functionalization leading to tailormade properties for a specific purpose. Here, the design of robust precursor polymer-decorated silica nano- and microparticles is demonstrated, which allows for easy post-modification by polymer embedded thiolactone chemistry. To obtain this organic-inorganic hybrid material, silica particles (SiO2P) were functionalized via surface-initiated atom transfer radical polymerization (SI-ATRP) with poly(2-hydroxyethyl acrylate) (PHEA)-poly(thiolactone acrylamide (PThlAm) co-polymer brushes. Exploiting the versatility of thiolactone post-modification, a system was developed that could be used in three exemplary applications: 1) the straightforward molecular post-functionalization to tune the surface polarity, and therefore the dispersibility in various solvents; 2) the immobilization of metal nanoparticles into the polymer brushes via the in situ formation of free thiols that preserved catalytic activity in a model reaction; 3) the formation of redox-responsive, permeable polymer capsules by crosslinking the thiolactone moieties with cystamine dihydrochloride (CDH) followed by dissolution of the silica core.

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Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

 

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In 2020.0 BIOMATERIALS published article about TUMOR MICROENVIRONMENT; FLUORESCENT-PROBE; NANOPARTICLES; ACTIVATION; SOFT in [Wang, Kun; Zhang, Huilin; Zhao, Peiran; Meng, Xianfu; Chen, Xiaoyan; Liu, Yang; Liu, Yanyan; Gong, Teng; Bu, Wenbo] East China Normal Univ, Coll Chem & Mol Engn, Shanghai Key Lab Green Chem & Chem Proc, 3663 North Zhongshan Rd, Shanghai 200062, Peoples R China; [Wu, Wanlu; Fang, Xiangming] Nanjing Med Univ, Wuxi Peoples Hosp, Dept Med Imaging, Nanjing, Peoples R China; [Shen, Aijun; Wang, Peijun] Tongji Univ, Tongji Hosp, Dept Med Imaging, Shanghai 200065, Peoples R China in 2020.0, Cited 44.0. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7. Category: thiazines

Glutathione (GSH) plays a vital role in maintaining biological redox homeostasis. Accordingly, accurate imaging of glutathione in vivo is of great significance. Herein, we propose a magnetic resonance energy transfer (MRET) strategy based on a distance-dependent magnetic exchange coupling effect (MECE), which can realize GSH detection within tumors in vivo by susceptibility weighted imaging (SWI). Fe3O4 nanoparticles (NPs) and CoFe2O4 NPs linked with cystamine (Fe3O4-S-S-CoFe2O4) have been successfully designed as SWI nanoprobes. After the disulfide bonds are broken by excess GSH in the tumor, the increase in the distance between Fe3O4 NPs and CoFe2O4 NPs will induce a decrease of MECE and magnetic susceptibility. As a result, the changes in the SWI signals are used for tumor GSH detection in vivo. Experimental results in vitro and in vivo demonstrate that the Fe3O4-S-S-CoFe2O4 SWI nanoprobe can sensitively detect concentrations of GSH in tumors. Hence, this strategy not only improves the sensitivity of the GSH response in SWI but also provides a powerful basis for the design of other responsive functional MRI nanoprobes.

Bye, fridends, I hope you can learn more about C4H14Cl2N2S2, If you have any questions, you can browse other blog as well. See you lster.. Category: thiazines

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

 

Extended knowledge of 2,2′-Disulfanediyldiethanamine dihydrochloride

Application In Synthesis of 2,2′-Disulfanediyldiethanamine dihydrochloride. Welcome to talk about 56-17-7, If you have any questions, you can contact Chen, CH; Chiang, CY; Wu, CW; Wang, CT; Chau, LK or send Email.

Application In Synthesis of 2,2′-Disulfanediyldiethanamine dihydrochloride. Authors Chen, CH; Chiang, CY; Wu, CW; Wang, CT; Chau, LK in MDPI published article about in [Chen, Chien-Hsing] Natl Pingtung Univ Sci & Technol, Dept Biomechatron Engn, Pingtung 91201, Taiwan; [Chiang, Chang-Yue] Natl Yunlin Univ Sci & Technol, Grad Sch Engn Sci & Technol, Touliu 64002, Yunlin, Taiwan; [Chiang, Chang-Yue; Wu, Chin-Wei] Natl Yunlin Univ Sci & Technol, Bachelor Program Interdisciplinary Studies, Touliu 64002, Yunlin, Taiwan; [Wang, Chien-Tsung] Natl Yunlin Univ Sci & Technol, Dept Chem & Mat Engn, Touliu 64002, Yunlin, Taiwan; [Chau, Lai-Kwan] Natl Chung Cheng Univ, Dept Chem & Biochem, Chiayi 62102, Taiwan; [Chau, Lai-Kwan] Natl Chung Cheng Univ, Ctr Nano Biodetect, Chiayi 62102, Taiwan in 2021.0, Cited 47.0. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7

In this research, a direct, simple and ultrasensitive fiber optic particle plasmon resonance (FOPPR) biosensing platform for immunoglobulin G (IgG) detection was developed using a gold nanoparticle/graphene oxide (AuNP/GO) composite as signal amplification element. To obtain the best analytical performance of the sensor, experimental parameters including the surface concentration of GO on the AuNPs, formation time of the GO, the concentration of the anti-IgG and incubation time of anti-IgG were optimized. The calibration plots displayed a good linear relationship between the sensor response (Delta I/I-0) and the logarithm of the analyte concentrations over a linear range from 1.0 x 10(-10) to 1.0 x 10(-6) g/mL of IgG under the optimum conditions. A limit of detection (LOD) of 0.038 ng/mL for IgG was calculated from the standard calibration curve. The plot has a linear relationship (correlation coefficient, R = 0.9990). The analytical performance of present work’s biosensor was better than that of our previously reported mixed self-assembled monolayer of 11-mercaptoundecanoic acid/6-mercapto-1-hexanol (MUA/MCH = 1:4) method by about three orders of magnitude. The achieved good sensitivity may be attributed to the synergistic effect between GO and AuNPs in this study. In addition, GO could immobilize more antibodies due to the abundant carboxylic groups on its surface. Furthermore, we also demonstrated that the results from this sensor have good reproducibility, with coefficients of variation (CVs) < 8% for IgG. Therefore, the present strategy provides a novel and convenient method for chemical and biochemical quantification and determination. Application In Synthesis of 2,2′-Disulfanediyldiethanamine dihydrochloride. Welcome to talk about 56-17-7, If you have any questions, you can contact Chen, CH; Chiang, CY; Wu, CW; Wang, CT; Chau, LK or send Email.

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

 

Chemistry Milestones Of 56-17-7

Formula: C4H14Cl2N2S2. Welcome to talk about 56-17-7, If you have any questions, you can contact Benda, D; Beck, S; Linscheid, MW or send Email.

An article Synthesis and characterization of a new MeCAT reagent containing a photocleavable linker for labeling of proteins and peptides in mass spectrometric analyses WOS:000449443900027 published article about QUANTITATIVE-PROTEOMICS; RELATIVE QUANTIFICATION; SULFENIC ACID; DERIVATIVES; RELEASE in [Benda, David; Beck, Sebastian; Linscheid, Michael W.] Humboldt Univ, Dept Chem, Brook Taylor Str 2, D-12489 Berlin, Germany in 2019.0, Cited 28.0. Formula: C4H14Cl2N2S2. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7

The quantification of proteins and peptides becomes more important besides mere identification in modern life sciences. Therefore, we have developed a new reagent that adds to the known metall-coded affinity tagging strategy employed in molecular and elemental mass spectrometry containing a photocleavable linker. A synthesis route was developed that provides the new reagent in good yields. The stability of the synthesized reagents was assessed under different temperature and illumination conditions. Labeling reactions were carried out at peptide and protein level, while also the fragmentation behavior of labeled peptides was assessed. In additional experiments, the photocleavability of the new reagent was examined. Upon irradiation with ultraviolet light, the photoproducts were liberated and could be used for quantification of labeled peptides.

Formula: C4H14Cl2N2S2. Welcome to talk about 56-17-7, If you have any questions, you can contact Benda, D; Beck, S; Linscheid, MW or send Email.

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

 

Final Thoughts on Chemistry for 56-17-7

Welcome to talk about 56-17-7, If you have any questions, you can contact Zhang, YB; Liu, SY; Li, TY; Zhang, LQ; Azhar, U; Ma, JC; Zhai, CC; Zong, CY; Zhang, SX or send Email.. Computed Properties of C4H14Cl2N2S2

Computed Properties of C4H14Cl2N2S2. In 2020.0 CARBOHYD POLYM published article about FOREIGN-BODY RESPONSE; GLYCOL) HYDROGELS; MICHAEL ADDITION; CROSS-LINKING; STEM-CELLS; RESISTANCE; COATINGS; RELEASE; CULTURE in [Zhang, Yabin; Liu, Shuyan; Li, Tianyu; Zhang, Luqing; Azhar, Umair; Ma, Jiachen; Zhai, Congcong; Zong, Chuanyong; Zhang, Shuxiang] Univ Jinan, Sch Chem & Chem Engn, Shandong Prov Key Lab Fluorine Chem & Chem Mat, Jinan 250022, Peoples R China in 2020.0, Cited 49.0. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7.

In this work, a facile click reaction strategy is employed to form hydrogels in situ with cytocompatibility, biodegradability, self-healing property and resistance to protein. The thiol-functionalized zwitterionic carboxybetaine methacrylate copolymer, which take part as a cross-linker in the thiol-ene click reaction with the methacrylated hyaluronic acid. The hydrogels are obtained under the physiological condition without the presence of any copper catalyst and UV light. The hydrogel consisting of zwitterionic component shows an obvious reduction in protein adsorption and cell adhesion and avoid non-targeted factor interference in the biological experiments. The hydrogels also demonstrate adjustable degradation behavior. Human mesenchymal stem cells (hMSCs) are easily encapsulated into the hydrogels and remains metabolically active, indicating the excellent biocompatibility of the hydrogels. Additionally, the result of the cytokine secretion assays (IL-6 and TNF-alpha) has shown that this clickable hydrogel can serve to suppress inflammatory reactions and is beneficial for in vivo applications. Based on the above results, this clickable hydrogel with excellent performance can be an amenable platform for 3D cell encapsulation.

Welcome to talk about 56-17-7, If you have any questions, you can contact Zhang, YB; Liu, SY; Li, TY; Zhang, LQ; Azhar, U; Ma, JC; Zhai, CC; Zong, CY; Zhang, SX or send Email.. Computed Properties of C4H14Cl2N2S2

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

 

When did you first realize you had a special interest and talent in2,2′-Disulfanediyldiethanamine dihydrochloride

Recommanded Product: 56-17-7. Welcome to talk about 56-17-7, If you have any questions, you can contact Curcio, M; Paoli, A; Cirillo, G; Di Pietro, S; Forestiero, M; Giordano, F; Mauro, L; Amantea, D; Di Bussolo, V; Nicoletta, FP; Iemma, F or send Email.

An article Combining Dextran Conjugates with Stimuli-Responsive and Folate-Targeting Activity: A New Class of Multifunctional Nanoparticles for Cancer Therapy WOS:000657027700001 published article about DRUG-DELIVERY; DOXORUBICIN; MICELLES; BEHAVIOR; CELL in [Curcio, Manuela; Paoli, Alessandro; Cirillo, Giuseppe; Forestiero, Martina; Giordano, Francesca; Mauro, Loredana; Amantea, Diana; Nicoletta, Fiore Pasquale; Iemma, Francesca] Univ Calabria, Dept Pharm Hlth & Nutr Sci, I-87036 Arcavacata Di Rende, Italy; [Di Pietro, Sebastiano; Di Bussolo, Valeria] Univ Pisa, Dept Pharm, Via Bonanno Pisano 33, I-56126 Pisa, Italy in 2021.0, Cited 42.0. Recommanded Product: 56-17-7. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7

Nanoparticles with active-targeting and stimuli-responsive behavior are a promising class of engineered materials able to recognize the site of cancer disease, targeting the drug release and limiting side effects in the healthy organs. In this work, new dual pH/redox-responsive nanoparticles with affinity for folate receptors were prepared by the combination of two amphiphilic dextran (DEX) derivatives. DEXFA conjugate was obtained by covalent coupling of the polysaccharide with folic acid (FA), whereas DEXssPEGCOOH derived from a reductive amination step of DEX was followed by condensation with polyethylene glycol 600. After self-assembling, nanoparticles with a mean size of 50 nm, able to be destabilized in acidic pH and reducing media, were obtained. Doxorubicin was loaded during the self-assembling process, and the release experiments showed the ability of the proposed system to modulate the drug release in response to different pH and redox conditions. Finally, the viability and uptake experiments on healthy (MCF-10A) and metastatic cancer (MDA-MB-231) cells proved the potential applicability of the proposed system as a new drug vector in cancer therapy.

Recommanded Product: 56-17-7. Welcome to talk about 56-17-7, If you have any questions, you can contact Curcio, M; Paoli, A; Cirillo, G; Di Pietro, S; Forestiero, M; Giordano, F; Mauro, L; Amantea, D; Di Bussolo, V; Nicoletta, FP; Iemma, F or send Email.

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

 

An update on the compound challenge: 2,2′-Disulfanediyldiethanamine dihydrochloride

Welcome to talk about 56-17-7, If you have any questions, you can contact Wang, F; Zhang, Q; Huang, KX; Li, JR; Wang, K; Zhang, K; Tang, XY or send Email.. COA of Formula: C4H14Cl2N2S2

An article Preparation and characterization of carboxymethyl cellulose containing quaternized chitosan for potential drug carrier WOS:000533508600136 published article about FACILE FABRICATION; HYDROGEL FILMS; DELIVERY; PH; MICELLES; RELEASE in [Wang, Fang; Zhang, Qian; Huang, Kexin; Li, Jiarui; Wang, Kun; Zhang, Kai; Tang, Xinyue] Nanjing Forestry Univ, Coll Chem Engn, Nanjing 210037, Jiangsu, Peoples R China; [Wang, Fang] Jiangsu Key Lab Chem & Utilizat Agr & Forest Biom, Nanjing, Jiangsu, Peoples R China in 2020.0, Cited 51.0. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7. COA of Formula: C4H14Cl2N2S2

The objective of this study was to synthesize and characterize cystamine dihydrochloride (CYS) crosslinked carboxymethyl cellulose/quaternized chitosan (CMC/HACC) composite hydrogel film. Firstly, the glycidyl-based quaternary ammonium chitosan derivative (HACC) was synthesized using nucleophilic substitution reaction. Then HACC was analyzed by FTIR, (HNMR)-H-1 spectra and the composite films at different blending ratio of CMC and HACC were studied by rheology measurement, mechanical and swelling tests. When the composite films were prepared under optimized conditions (CMC: HACC = 7:1), they showed excellent mechanical properties (with improved 93.3% tensile strength and 2.3% elongation at break) and swellability (equilibrium swelling ratio increased 270%) compared to pure CMC film. 5-Fluorouracil (5-FU) was used as drug model which has broad-spectrum anticancer properties. The 5-FU/CMC/HACC composite films showed redox and pH responsive of drug release properties along with well biocompatibility. The in vitro cytotoxicity and cell apoptosis studies showed the drug loaded composite films with obvious toxicity against HepG2 cells especially in the presence of GSH. In addition, CMC/HACC composite films showed good antibacterial against S. aureus and E. coli, while pure CMC film had no antimicrobial activities. It can be concluded that CMC/HACC composite films can be potentially used as targeted drug delivery system. (C) 2019 Elsevier B.V. All rights reserved.

Welcome to talk about 56-17-7, If you have any questions, you can contact Wang, F; Zhang, Q; Huang, KX; Li, JR; Wang, K; Zhang, K; Tang, XY or send Email.. COA of Formula: C4H14Cl2N2S2

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem