I found the field of Polymer Science very interesting. Saw the article Bioinspired glycosaminoglycan hydrogels via click chemistry for 3D dynamic cell encapsulation published in 2019.0. COA of Formula: C4H14Cl2N2S2, Reprint Addresses Deng, M (corresponding author), Purdue Univ, Dept Agr & Biol Engn, W Lafayette, IN 47907 USA.; Deng, M (corresponding author), Purdue Univ, Bindley Biosci Ctr, W Lafayette, IN 47907 USA.; Deng, M (corresponding author), Purdue Univ, Sch Mat Engn, W Lafayette, IN 47907 USA.; Deng, M (corresponding author), Purdue Univ, Weldon Sch Biomed Engn, W Lafayette, IN 47907 USA.. The CAS is 56-17-7. Through research, I have a further understanding and discovery of 2,2′-Disulfanediyldiethanamine dihydrochloride
Cell encapsulation within 3D hydrogels is an attractive approach to develop effective cell-based therapies. However, little is known about how cells respond to the dynamic microenvironment resulting from hydrogel gelation-based cell encapsulation. Here, a tunable biomimetic hydrogel system that possesses alterable gelation kinetics and biologically relevant matrix stiffness is developed to study 3D dynamic cellular responses during encapsulation. Hydrogels are synthesized by crosslinking thiolated hyaluronic acid and thiolated chondroitin sulfate with poly(ethylene glycol) diacrylate under cell-compatible conditions. Hydrogel properties are tailored by altering thiol substitution degrees of glycosaminoglycans or molecular weights of crosslinkers. Encapsulation of human mesenchymal stem cells through hydrogel gelation reveals high cell viability as well as a three-stage gelation-dependent cellular response in real-time focal adhesion kinase (FAK) phosphorylation in live single cells. Furthermore, stiffer hydrogels result in higher equilibrium FAK activity and enhanced actin protrusions. Our results demonstrate the promise of hydrogel-mediated cellular responses during cell encapsulation. (c) 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47212.
Welcome to talk about 56-17-7, If you have any questions, you can contact Kuang, LJ; Damayanti, NP; Jiang, CH; Fei, X; Liu, WJ; Narayanan, N; Irudayaraj, J; Campanella, O; Deng, M or send Email.. COA of Formula: C4H14Cl2N2S2
Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem