Can You Really Do Chemisty Experiments About 2,2′-Disulfanediyldiethanamine dihydrochloride

Welcome to talk about 56-17-7, If you have any questions, you can contact Narayanan, N; Jia, ZH; Kim, KH; Kuang, LJ; Lengemann, P; Shafer, G; Bernal-Crespo, V; Kuang, SH; Deng, M or send Email.. COA of Formula: C4H14Cl2N2S2

I found the field of Engineering; Materials Science very interesting. Saw the article Biomimetic glycosaminoglycan-based scaffolds improve skeletal muscle regeneration in a Murine volumetric muscle loss model published in 2021.0. COA of Formula: C4H14Cl2N2S2, Reprint Addresses Deng, M (corresponding author), Purdue Univ, Dept Agr & Biol Engn, Sch Mat Engn, Weldon Sch Biomed Engn,Bindley Biosci Ctr, W Lafayette, IN 47907 USA.. The CAS is 56-17-7. Through research, I have a further understanding and discovery of 2,2′-Disulfanediyldiethanamine dihydrochloride

Volumetric muscle loss (VML) injuries characterized by critical loss of skeletal muscle tissues result in severe functional impairment. Current treatments involving use of muscle grafts are limited by tissue availability and donor site morbidity. In this study, we designed and synthesized an implantable glycosaminoglycan-based hydrogel system consisting of thiolated hyaluronic acid (HA) and thiolated chondroitin sulfate (CS) crosslinked with poly(ethylene glycol) diacrylate to promote skeletal muscle regeneration of VML injuries in mice. The HA-CS hydrogels were optimized with suitable biophysical properties by fine-tuning degree of thiol group substitution to support C2C12 myoblast proliferation, myogenic differentiation and expression of myogenic markers MyoD, MyoG and MYH8. Furthermore, in vivo studies using a murine quadriceps VML model demonstrated that the HA-CS hydrogels supported integration of implants with the surrounding host tissue and facilitated migration of Pax7(+) satellite cells, de novo myofiber formation, angiogenesis, and innervation with minimized scar tissue formation during 4-week implantation. The hydrogel-treated and autograft-treated mice showed similar functional improvements in treadmill performance as early as 1-week post-implantation compared to the untreated groups. Taken together, our results demonstrate the promise of HA-CS hydrogels as regenerative engineering matrices to accelerate healing of skeletal muscle injuries.

Welcome to talk about 56-17-7, If you have any questions, you can contact Narayanan, N; Jia, ZH; Kim, KH; Kuang, LJ; Lengemann, P; Shafer, G; Bernal-Crespo, V; Kuang, SH; Deng, M or send Email.. COA of Formula: C4H14Cl2N2S2

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem