Recently I am researching about FOREIGN-BODY RESPONSE; GLYCOL) HYDROGELS; MICHAEL ADDITION; CROSS-LINKING; STEM-CELLS; RESISTANCE; COATINGS; RELEASE; CULTURE, Saw an article supported by the Natural Science Foundation of Shandong Province of ChinaNatural Science Foundation of Shandong Province [ZR2018BC026]; Major Program of Shandong Province Natural Science Foundation [ZR2017ZC0529]; Key Research and Development Program of Shandong Province of China [2019GGX102005, 2019GGX102030]. Published in ELSEVIER SCI LTD in OXFORD ,Authors: Zhang, YB; Liu, SY; Li, TY; Zhang, LQ; Azhar, U; Ma, JC; Zhai, CC; Zong, CY; Zhang, SX. The CAS is 56-17-7. Through research, I have a further understanding and discovery of 2,2′-Disulfanediyldiethanamine dihydrochloride. Quality Control of 2,2′-Disulfanediyldiethanamine dihydrochloride
In this work, a facile click reaction strategy is employed to form hydrogels in situ with cytocompatibility, biodegradability, self-healing property and resistance to protein. The thiol-functionalized zwitterionic carboxybetaine methacrylate copolymer, which take part as a cross-linker in the thiol-ene click reaction with the methacrylated hyaluronic acid. The hydrogels are obtained under the physiological condition without the presence of any copper catalyst and UV light. The hydrogel consisting of zwitterionic component shows an obvious reduction in protein adsorption and cell adhesion and avoid non-targeted factor interference in the biological experiments. The hydrogels also demonstrate adjustable degradation behavior. Human mesenchymal stem cells (hMSCs) are easily encapsulated into the hydrogels and remains metabolically active, indicating the excellent biocompatibility of the hydrogels. Additionally, the result of the cytokine secretion assays (IL-6 and TNF-alpha) has shown that this clickable hydrogel can serve to suppress inflammatory reactions and is beneficial for in vivo applications. Based on the above results, this clickable hydrogel with excellent performance can be an amenable platform for 3D cell encapsulation.
Quality Control of 2,2′-Disulfanediyldiethanamine dihydrochloride. About 2,2′-Disulfanediyldiethanamine dihydrochloride, If you have any questions, you can contact Zhang, YB; Liu, SY; Li, TY; Zhang, LQ; Azhar, U; Ma, JC; Zhai, CC; Zong, CY; Zhang, SX or concate me.
Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem