Day: October 19, 2021

Product Details of 56-17-7. Javorskis, T; Jurys, A; Bagdziunas, G; Orentas, E in [Javorskis, Tomas; Jurys, Arminas; Orentas, Edvinas] Vilnius Univ, Dept Organ Chem, Naugarduko 24, LT-03225 Vilnius, Lithuania; [Javorskis, Tomas; Bagdziunas, Gintautas] Ctr Phys Sci & Technol, Sauletekio Av 3, LT-10257 Vilnius, Lithuania; [Bagdziunas, Gintautas] Vilnius Univ, Life Sci Ctr, Inst Biochem, Sauletekio Av 7, LT-10257 Vilnius, Lithuania published Synthesis of C- and N-Substituted 1,5,2,6-Dithiadiazocanes -Electrophilic-Nucleophilic Thioamination (ENTA) Reagents in 2021.0, Cited 38.0. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7.

A synthetic method is presented for S-N bond formation starting from cheap and affordable materials. We show that (un)substituted N-protected cyclic eight-membered C-2-symmetric sulfenamides have been prepared in a few steps using this procedure. The synthetic utility of these ambipolar derivatives was demonstrated in a variety of synthetic transformations affording different S,N-heterocyles of pharmaceutical relevance in one or two steps from simple starting materials.

Product Details of 56-17-7. About 2,2′-Disulfanediyldiethanamine dihydrochloride, If you have any questions, you can contact Javorskis, T; Jurys, A; Bagdziunas, G; Orentas, E or concate me.

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

I found the field of Polymer Science very interesting. Saw the article Aminolysis induced functionalization of (RAFT) polymer-dithioester with thiols and disulfides published in 2020.0. Quality Control of 2,2′-Disulfanediyldiethanamine dihydrochloride, Reprint Addresses Schlaad, H (corresponding author), Univ Potsdam, Inst Chem, Karl Liebknecht Str 24-25, D-14476 Potsdam, Germany.. The CAS is 56-17-7. Through research, I have a further understanding and discovery of 2,2′-Disulfanediyldiethanamine dihydrochloride

A series of polystyrene- and poly(methyl methacrylate)-dithioesters was subjected to aminolysis under ambient atmospheric conditions, i.e., in the presence of oxygen. Polymer disulfide coupling by oxidation occurred within tens of minutes and the yield of disulfide-coupled polymer increased with decreasing polymer molar mass. Oxidation of thiolates is usually an unwanted side reaction, here it is employed to obtain exclusively polymeric mixed disulfides through in situ aminolysis/functionalization in the presence of a thiol. The in situ aminolysis/functionalization in the presence of a disulfide, Ellman’s reagent or polymer disulfide, resulted in the exclusive formation of polymer-dithionitrobenzoic acid, which can be further reacted with a thiol to exchange the terminal functionality, or block copolymer with dynamic disulfide linker, respectively.

Quality Control of 2,2′-Disulfanediyldiethanamine dihydrochloride. About 2,2′-Disulfanediyldiethanamine dihydrochloride, If you have any questions, you can contact Hess, A; Schmidt, BVKJ; Schlaad, H or concate me.

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

An article Soft poly(N-vinylcaprolactam) nanogels surface-decorated with AuNPs. Response to temperature, light, and RF-field WOS:000471736400008 published article about VINYLCAPROLACTAM-BASED MICROGELS; PHASE-TRANSITION BEHAVIOR; GOLD CLUSTER MOLECULES; N-VINYLCAPROLACTAM; 1-ANILINO-8-NAPHTHALENE SULFONATE; NANOPARTICLES; FLUORESCENCE; POLYMERS; RELEASE; DELIVERY in [Siirila, Joonas; Karesoja, Mikko; Pulkkinen, Petri; Tenhu, Heikki] Univ Helsinki, Dept Chem, PB 55, FIN-00014 Helsinki, Finland; [Malho, Jani-Markus] Aalto Univ, Dept Appl Phys, FI-00076 Espoo, Finland in 2019.0, Cited 64.0. Computed Properties of C4H14Cl2N2S2. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7

Soft poly(N-vinylcaprolactam) (PNVCL) based nanogels were prepared and surface-decorated with gold nanoparticles (AuNPs). The applicability of the hybrid nanogels (PNVCL-AuNPs) as carriers for low molar mass substances was of special interest. AuNPs protected with a mixture of 11-azidoundecanothiol and 11-mercaptoundecanoic acid were bound to propargyl functionalized PNVCL based nanogels. Acidic groups on the surfaces of AuNPs and PNVCL based nanogels stabilize the particle dispersions against precipitation above the phase transition temperature of PNVCL. Both the neat PNVCL nanogels and the PVCL-AuNPs shrink upon heating the dispersions. Even though the AuNPs are mainly located in the soft surface layer of the nanogels, the PNVCL-AuNPs respond to visible light as well as to radio-frequency (RF) irradiation by shrinking due to the AuNPs acting as nanoheaters. Interactions of linear PNVCL, PNVCL nanogels and PNVCL-AuNPs with two fluorescent probes were studied as function of increasing temperature. Once bound to the polymer the fluorescent probe may or may not be released from it, depending on its polarity and water solubility. Presence of AuNPs changed the release behavior of the water soluble charged fluorescent probe from the nanogels.

Computed Properties of C4H14Cl2N2S2. About 2,2′-Disulfanediyldiethanamine dihydrochloride, If you have any questions, you can contact Siirila, J; Karesoja, M; Pulkkinen, P; Malho, JM; Tenhu, H or concate me.

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

Ma, D; Shi, MH; Li, X; Zhang, JL; Fan, Y; Sun, K; Jiang, TT; Peng, C; Shi, XY in [Ma, Dan; Zhang, Jiulong; Peng, Chen; Shi, Xiangyang] Tongji Univ, Sch Med, Shanghai Peoples Hosp 10, Canc Ctr, Shanghai 200072, Peoples R China; [Ma, Dan; Shi, Menghan; Li, Xin; Fan, Yu; Jiang, Tingting; Shi, Xiangyang] Donghua Univ, Coll Chem Chem Engn & Biotechnol, Shanghai 201620, Peoples R China; [Sun, Kai] Univ Michigan, Dept Mat Sci & Engn, Ann Arbor, MI 48109 USA; [Peng, Chen] Ninghai First Hosp, Ningbo 315600, Peoples R China published Redox-Sensitive Clustered Ultrasmall Iron Oxide Nanoparticles for Switchable T-2/T-1-Weighted Magnetic Resonance Imaging Applications in 2020.0, Cited 44.0. SDS of cas: 56-17-7. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7.

Development of novel activable dual-mode T-1/T-2-weighted magnetic resonance (MR) contrast agents with the same composition for dynamic precision imaging of tumors has been a challenging task. Here, we demonstrated a strategy to prepare clustered Fe3O4 nanoparticles (NPs) with redox-responsiveness to tumor microenvironment to achieve switchable T-2/T-1-weighted dual-mode MR imaging applications. In this study, we first synthesized ultrasmall Fe3O4 NPs with an average size of 3.3 nm and an r, relaxivity of 4.3 mM(-1) s(-1), and then cross-linked the single Fe3O4 NPs using cystamine dihydrochloride (Cys) to form clustered Fe3O4/Cys NPs. The Fe3O4 nanoclusters (NCs) possess desirable colloidal stability, cytocompatibility, high r(2) relaxivity (26.4 mM(-1) s(-1)), and improved cellular uptake efficiency. Importantly, with the redox-responsiveness of the disulfide bond of Cys, the Fe3O4 NCs can be dissociated to form single particles under a reducing condition, hence displaying a switchable T-2/T-1-weighted MR imaging property that can be utilized for dynamic precision imaging of cancer cells in vitro and a subcutaneous tumor model in vivo due to the reductive intracellular environment of cancer cells and the tumor microenvironment. With the tumor reductive microenvironment-mediated switching of T-2 to T-1 MR effect and the ultrasmall size of the single particles that can pass through the kidney filter, the developed Fe3O4 NCs may be used as a promising switchable T-2/T-1 dual-mode MR contrast agent for precision imaging of different biosystems.

About 2,2′-Disulfanediyldiethanamine dihydrochloride, If you have any questions, you can contact Ma, D; Shi, MH; Li, X; Zhang, JL; Fan, Y; Sun, K; Jiang, TT; Peng, C; Shi, XY or concate me.. SDS of cas: 56-17-7

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

An article Cyclic telluride reagents with remarkable glutathione peroxidase-like activity for purification-free synthesis of highly pure organodisulfides WOS:000475507500027 published article about AEROBIC OXIDATION; ORGANOSELENIUM COMPOUND; PERMANGANATE OXIDATION; ANTIOXIDANT CAPACITY; SELECTIVE OXIDATION; EFFICIENT SYNTHESIS; THIOLS; DISULFIDES; ISOMERASE; CATALYST in [Arai, Kenta; Osaka, Yuui; Haneda, Masahiro; Sato, Yuumi] Tokai Univ, Dept Chem, Sch Sci, Hiratsuka, Kanagawa 2591292, Japan in 2019.0, Cited 60.0. Quality Control of 2,2′-Disulfanediyldiethanamine dihydrochloride. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7

Monoamino cyclic tellurides with a five-or six-membered ring structure and their derivatives were developed as a new class of catalyst for the oxidation of organothiols to organodisulfides in a glutathione peroxidase-like catalytic reaction. Quantitative conversion and high reaction rate were achieved by performing the reaction in an organic-aqueous segmented microflow system. Importantly, the process circumvented product purification, which is a major limitation of current organodisulfide synthetic methods.

About 2,2′-Disulfanediyldiethanamine dihydrochloride, If you have any questions, you can contact Arai, K; Osaka, Y; Haneda, M; Sato, Y or concate me.. Quality Control of 2,2′-Disulfanediyldiethanamine dihydrochloride

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

Jeong, C; Kim, J; Kim, YC in [Jeong, Chanuk; Kim, Juhwan; Kim, Yeu-Chun] Korea Adv Inst Sci & Technol KAIST, Dept Chem & Biomol Engn, Daejeon, South Korea; [Kim, Yeu-Chun] Korea Adv Inst Sci & Technol KAIST, KAIST Inst Hlth Sci & Technol, Daejeon, South Korea published Fluorescence color-changeable branched-form heptamethine cyanine dye as a redox-responsive multi-functional drug delivery system for enhanced cancer diagnosis and chemophototherapy in 2020.0, Cited 20.0. Application In Synthesis of 2,2′-Disulfanediyldiethanamine dihydrochloride. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7.

A multifunctional drug delivery system (MDDS) based on near-infrared (NIR) imaging was developed in various conformations for the accurate diagnosis and therapy of cancer. However, it remains challenging to develop an ideal structure for an MDDS with both exact and variable functionality. Herein, we report a fluorescence color-changeable branched-form heptamethine cyanine dye (PEG-4-CyP) that has both a simple structure and various functionality. The PEG-4-CyP was not only able to construct the nanoparticle (NP) structure by encapsulating DOX (PEG-4-CyP/DOX), but also showed change in the NIR fluorescence color by reacting with glutathione (GSH). The PEG-4-CyP/DOX was broken down in the redox microenvironment inside cancers because of the reduction reaction of PEG-4-CyP to GSH. As a result, the NP disruption, DOX release, and reactivity of PEG-4-CyP to GSH were visualized by NIR fluorescence color-change. Moreover, PEG-4-CyP/DOX showed an excellent chemophototherapeutic effect in cancer cells. This NIR fluorescence color-change strategy demonstrates the applicability of PEG-4-CyP as a novel MDDS able to provide a variety of information with a simple NP structure. (C) 2020 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.

About 2,2′-Disulfanediyldiethanamine dihydrochloride, If you have any questions, you can contact Jeong, C; Kim, J; Kim, YC or concate me.. Application In Synthesis of 2,2′-Disulfanediyldiethanamine dihydrochloride

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

Authors Arai, K; Sato, Y; Nakajima, I; Saito, M; Sasaki, M; Kanamori, A; Iwaoka, M in PERGAMON-ELSEVIER SCIENCE LTD published article about in [Arai, Kenta; Sato, Yuumi; Nakajima, Ikumi; Saito, Manami; Sasaki, Moeka; Iwaoka, Michio] Tokai Univ, Sch Sci, Dept Chem, Hiratsuka, Kanagawa 2591292, Japan; [Kanamori, Akiko] Tokai Univ, Dept Appl Biochem, Hiratsuka, Kanagawa 2591292, Japan; [Kanamori, Akiko] Tokai Univ, Inst Adv Biosci, Hiratsuka, Kanagawa 2591292, Japan in 2021.0, Cited 55.0. Computed Properties of C4H14Cl2N2S2. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7

Amphiphilic derivatives of (+/-)-trans-1,2-diselenane-4,5-diol (DSTox) decorated with long alkyl chains or aromatic substituents via ester linkages were applied as glutathione peroxidase (GPx)-like catalysts. The reduction of H2O2 with the diselenide catalysts was accelerated through a GPx-like catalytic cycle, in which the diselenide (Se-Se) bond was reduced to the diselenolate form ([Se-,Se-]) by coexisting dithiothreitol, and the generated highly active [Se-,Se-] subsequently reduced H2O2 to H2O retrieving the original Se-Se form. In the lipid peroxidation of lecithin/cholesterol liposomes induced by 2,2′-azobis(2-amidinopmpane) dihydrochloride (AAPH), on the other hand, the Se-Se form directly reduced lipid peroxide (LOOH) to the corresponding alcohol (LOH), inhibiting the radical chain reaction, to exert the antioxidative effect. Thus, the two GPx-like catalytic cycles can be switched depending on the peroxide substrates. Furthermore, hydrophilic compounds with no or short alkyl groups (C3) showed high antioxidative activities for the catalytic reduction of H2O2, while lipophilic compounds with long alkyl chains (C6-C14) or aromatic substituents were more effective antioxidants against lipid peroxidation. In addition, these compounds showed low cytotoxicity in cultured HeLa cells and exhibited sufficient anti-lipid peroxidative activities, suggesting their potentials as selenium-based antioxidative drugs.

About 2,2′-Disulfanediyldiethanamine dihydrochloride, If you have any questions, you can contact Arai, K; Sato, Y; Nakajima, I; Saito, M; Sasaki, M; Kanamori, A; Iwaoka, M or concate me.. Computed Properties of C4H14Cl2N2S2

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

Authors Yang, X; Cheng, Q; Monnier, V; Charles, L; Karoui, H; Ouari, O; Gigmes, D; Wang, RB; Kermagoret, A; Bardelang, D in WILEY-V C H VERLAG GMBH published article about in [Yang, Xue; Charles, Laurence; Karoui, Hakim; Ouari, Olivier; Gigmes, Didier; Kermagoret, Anthony; Bardelang, David] Aix Marseille Univ, CNRS, ICR, Marseille, France; [Cheng, Qian; Wang, Ruibing] Univ Macau, Inst Chinese Med Sci, State Key Lab Qual Res Chinese Med, Ave Univ, Taipa, Macau, Peoples R China; [Monnier, Valerie] Aix Marseille Univ, CNRS, Cent Marseille, FSCM,Spectropole, Marseille, France in 2021.0, Cited 87.0. HPLC of Formula: C4H14Cl2N2S2. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7

Molecular machines are ubiquitous in nature and function away from equilibrium by consuming fuels to produce appropriate work. Chemists have recently excelled at mimicking the fantastic job performed by natural molecular machines with synthetic systems soluble in organic solvents. In efforts toward analogous systems working in water, we show that guest molecules can be exchanged in the synthetic macrocycle cucurbit[7]uril by involving kinetic traps, and in such a way as modulating energy wells and kinetic barriers using pH, light, and redox stimuli. Ditolyl-viologen can also be exchanged using the best kinetic trap and interfaced with alginate, thus affording pH-responsive blue, fluorescent hydrogels. With tunable rate and binding constants toward relevant guests, cucurbiturils may become excellent ring molecules for the construction of advanced molecular machines working in water.

HPLC of Formula: C4H14Cl2N2S2. About 2,2′-Disulfanediyldiethanamine dihydrochloride, If you have any questions, you can contact Yang, X; Cheng, Q; Monnier, V; Charles, L; Karoui, H; Ouari, O; Gigmes, D; Wang, RB; Kermagoret, A; Bardelang, D or concate me.

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

An article High Sensitive Detection of Prostate Specific Antigen by Using Ferrocene Cored Asymmetric PAMAM Dendrimer Interface Screen Printed Electrodes WOS:000456285500005 published article about ELECTROCHEMICAL IMMUNOSENSOR; GOLD NANOPARTICLES; CANCER DETECTION; PSA; BIOMARKER; BIOSENSOR; IMMOBILIZATION; NANOMATERIALS; NANOTUBES; MORTALITY in [Cevik, Emre] Imam Abdulrahman Bin Faisal Univ, IRMC, Dept Genet Res, POB 1982, Dammam 31441, Saudi Arabia in 2019.0, Cited 43.0. Computed Properties of C4H14Cl2N2S2. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7

In this study, electrochemical immunosensors were developed for the detection of prostate specific antigen (PSA) using ferrocene (Fc) and polyamidoamine dendrimer (PAMAM) constructs. The biosensor fabrication was designed by modifying the screen-printed gold electrode (Au) with ferrocene cored dendrimers (FcPAMAM) synthesized in three different generations. The self-assembled monolayer principle was followed, to obtain sensitive, selective and disposable electrodes. Therefore, the Au electrodes were modified with cysteamine (Cys) to obtain a functional surface for FcPAMAM dendrimers to bind. Dendrimer generations were attached to this surface using a cross-linker (glutaraldehyde) so that a suitable surface was obtained for binding of biological components. The Monoclonal PSA antibody (anti-PSA) was immobilized on the Au electrode surface which coated with dendrimer, and (Au/Cys/FcPAMAM/anti-PSA) biosensing electrode was obtained. The PSA detection performances of electrochemical impedance spectroscopy (EIS) and Amperometry based immunosensors exhibited very low detection limits; 0.001 ng mL(-1) and 0.1 pg mL(-1), respectively. In addition, EIS and Amperometry based biosensors using Au/Cys/FcPAMAM/anti-PSA sensing electrode were represented excellent linear ranges of 0.01 ng mL(-1) to 100 ng mL(-1) and 0.001 ng mL(-1) to 100 ng mL(-1). In order to determine the applicability recovery and selectivity tests were performed using three different proteins in human serum.

Computed Properties of C4H14Cl2N2S2. About 2,2′-Disulfanediyldiethanamine dihydrochloride, If you have any questions, you can contact Cevik, E or concate me.

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

Authors Pinter, ZW; Farnell, CG; Huntley, S; Patel, HA; Peng, JG; McMurtrie, J; Ray, JL; Naranje, S; Shah, AB in SPRINGER HEIDELBERG published article about STRESS-FRACTURES; INJURIES in [Pinter, Zachariah W.; Farnell, Chason G.; Huntley, Samuel; Patel, Harshadkumar A.; Peng, Jianguang; McMurtrie, James; Ray, Jessyca L.; Naranje, Sameer; Shah, Ashish B.] Univ Alabama Birmingham, Dept Orthopaed Surg, 1313 13th St South, Birmingham, AL 35205 USA in 2020.0, Cited 20.0. Name: 2,2′-Disulfanediyldiethanamine dihydrochloride. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7

Background Turf toe injuries, though most common in athletes, can also occur in non-athletes. No study exists in the current literature investigating operative outcomes in non-athlete patients with chronic turf toe injury. In this study, we present our outcomes on operatively treated turf toe injuries in non-athletes in the only cohort yet studied. Methods Using ICD-10 codes, we assembled a cohort of 12 patients who underwent operative repair of chronic turf toe injury from January 2012 through January 2018 at the investigating institution. These 12 patients were evaluated to determine demographic information, method of injury, length of time from injury to surgery, clinical and radiologic characteristics of the injury, and operative outcomes including mean preoperative and postoperative VAS (Visual Analog Scale) scores, preoperative and postoperative FFI (Foot Function Index) scores, and postoperative complications. Results On initial clinical presentation, all 12 patients had local tenderness with associated painful range of motion. Four patients had restricted range of motion, all patients had a positive Lachman test, two had local edema, and eight had hallux valgus deformity. Mean VAS improved from 4.6 (range 2-9) to 1 (range 0-4). Mean FFI improved from 102.5 (range 56-177) to 61.75 (range 23-144). All patients had a negative Lachman test at final follow-up. No patients developed major complications or required revision surgery. Conclusions Our study is the first to investigate operative outcomes following chronic turf toe injury in non-athlete patients. Based on our study, surgeons and patients can expect significant improvement in overall pain and function following surgery.

Name: 2,2′-Disulfanediyldiethanamine dihydrochloride. About 2,2′-Disulfanediyldiethanamine dihydrochloride, If you have any questions, you can contact Pinter, ZW; Farnell, CG; Huntley, S; Patel, HA; Peng, JG; McMurtrie, J; Ray, JL; Naranje, S; Shah, AB or concate me.

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem