151-21-3, molecular formula is C12H25NaO4S, molweight is 288.3793(g/mol), SMILES CODE is O=S(OCCCCCCCCCCCC)([O-])=O.[Na+]. In this document, Reinvestigations into synthesis of allyldithiocarbamates and their intramolecular cyclization: synthesis and antihyperglycemic activity of 2-thioxothiazolidine-4-alkanoates. Application In Synthesis of Sodium dodecyl sulfate.
Reinvestigations into synthesis of allyldithiocarbamates and their intramolecular cyclization: synthesis and antihyperglycemic activity of 2-thioxothiazolidine-4-alkanoates
Reinvestigating the synthesis of allylthiocarbamates from MBH derivatives revealed that they are obtained more efficiently from allylbromides in isopropanol rather than acetates in water. Further unlike reported, the base-mediated intramolecular cyclization of these allyldithiocarbamates give substituted 2-thioxothiazolidine-4-alkanoates instead of substituted 1,3-thiazines and the reaction was restricted to 2- or 4-nitrophenyl carrying substrates. Screening of these products for antihyperglycemic activity revealed that 5bC displays significant activity via partial agonist activity on PPAR gamma at transcriptional level, which was corroborated by molecular docking studies. (C) 2014 Elsevier Ltd. All rights reserved.
Application In Synthesis of Sodium dodecyl sulfate, The potential utility of systematic synthetic strategy will be applicable to efficient generations of chemical libraries of compounds to find ‘hit’ molecules.Read on for other articles about 151-21-3.
Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem