Why do aromatic interactions matter? In this blog, let’s explore why it’s so important to understand aromatic interactions using C12H25NaO4S, , Category: thiazines, 151-21-3, Name is Sodium dodecyl sulfate, molecular formula is C12H25NaO4S, belongs to thiazines compound. In a document, author is Li, Chun-Shun, introduce the new discover.
A New Metabolite with a Unique 4-Pyranone-gamma-Lactam-1,4-Thiazine Moiety from a Hawaiian-Plant Associated Fungus
An endophytic fungus Paraphaeosphaeria neglecta FT462 isolated from the Hawaiian-plant Lycopodiella cernua (L.) Pic. Serm produced one unusual compound (1, paraphaeosphaeride A) with the 4-pyranone-gamma-lactam-1,4-thiazine moiety, along With two new compounds (2 and 3, paraphaeosphaerides B and C, respectively) and the known compound (4). Compounds 1-3 were characterized by NMR and MS spectroscopic analysis. The absolute configuration of the 3-position of compound 1 was determined as S by electronic circular dichroism (ECD) calculations. Compound 3 also Showed STAT3 inhibition at 10 mu M.
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Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem