Career opportunities within science and technology are seeing unprecedented growth across the world, and those who study chemistry or another natural science at university now have increasingly better career prospects. , Electric Literature of 5326-23-8, 5326-23-8, Name is 6-Chloronicotinic acid, molecular formula is C6H4ClNO2, belongs to thiazines compound. In a document, author is Mahmoud, Huda K., introduce the new discover.
Synthesis and characterization of some novel bis-thiazoles
The bis-thiosemicarbazone derivative 3 was prepared and reacted with N-aryl-2-oxopropane hydrazonoyl chloride 4a-g and ethyl (N-arylhydrazono)chloroacetate 7a-e in absolute ethanol in the presence of triethylamine at reflux afforded a new series of thiazoles 6a-g and 9a-e, respectively. Also, thiosemicarbazone derivative 3 was reacted with N ‘-phenylbenzohydrazonoyl chloride 10 to give the respective bis-thiadiazole derivative 12. Moreover, the reaction of 3 with a number of haloketones and haloesters furnished the respective bis-thiazole derivatives 14, 16, 18, and 20. The mechanisms that account for formation of products 6, 9, and 12 were discussed. Also, the molecular structure of the synthesized compounds was illustrated by spectroscopic and elemental analysis.
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Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem