Career opportunities within science and technology are seeing unprecedented growth across the world, and those who study chemistry or another natural science at university now have increasingly better career prospects. , HPLC of Formula: https://www.ambeed.com/products/154445-78-0.html, 154445-78-0, Name is 2,2,4,6,7-Pentamethyl-2,3-dihydrobenzofuran-5-sulfonyl chloride, molecular formula is C13H17ClO3S, belongs to thiazines compound. In a document, author is Barange, Deepak Kumar, introduce the new discover.
Regioselective synthesis of thiophene fused sultam derivatives via iodocyclization approach and their application towards triazole linker
An efficient regioselective synthesis of 4-iodo-2,3-disubstituted-2H-thieno[3,2-el[1,2]thiazine-1,1-dioxide derivatives via iodocyclization approach using iodine under mild reaction condition described herein. This coupling iodocyclization strategy tolerated a variety of functional groups such as alkyl, cycloalkyl, phenyl producing the six-membered heterocyclic ring selectively. The resulting 4-iodo-2,3disubstituted-2H-thieno[3,2-e][1,2]thiazine-1,1-dioxide was coupled with a variety of boronic acids (Suzuki coupling) and activated alkenes (Heck coupling). The iodo group was utilized for Sonogashira coupling followed by efficient transformation to azido precursor, which was used for the synthesis of various thieno-sultam linked with triazole. (C) 2014 Elsevier Ltd. All rights reserved.
HPLC of Formula: https://www.ambeed.com/products/154445-78-0.html, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 154445-78-0.
Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem