New Advances in Chemical Research, May 2021. We’ll be discussing some of the latest developments in chemical about CAS: 6192-52-5, Name is 4-Methylbenzenesulfonic acid hydrate, belongs to thiazines compound, is a common compound. In a pantent, author is Guan, Zong, once mentioned the new application about 6192-52-5, Application In Synthesis of 4-Methylbenzenesulfonic acid hydrate.
Organic Synthesis with N-Heterocyclic Carbenes of Indazole: Synthesis of Benzo(thio)imidates, Benzo[d][1,3]thiazines and Quinazoline-4-thiones
The N-heterocyclic carbenes of indazole, generated by deprotonation of indazolium salts, proved to be versatile starting materials for organic synthesis. They undergo ring-opening reactions to generate ketenimines which readily add thiols thus affording what are, to the best of our knowledge, the first examples of 2-anilinobenzothioimidates. Water converts the ring-opened intermediates into functionalized 2-anilinobenzamides which can be thionated with Lawesson’s reagent and subsequently cyclized with formaldehyde and propionaldehyde, respectively, to give benzo[d][1,3]thiazines and quinazoline-4-thiones. The outcome of the cyclization depends upon the thiobenzamide substitution pattern.
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 6192-52-5. The above is the message from the blog manager. Application In Synthesis of 4-Methylbenzenesulfonic acid hydrate.
Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem