Career opportunities within science and technology are seeing unprecedented growth across the world, and those who study chemistry or another natural science at university now have increasingly better career prospects. , Safety of Sodium methanesulfinate, 20277-69-4, Name is Sodium methanesulfinate, molecular formula is CH3NaO2S, belongs to thiazines compound. In a document, author is Wen, Li-Rong, introduce the new discover.
Dual Roles of beta-Oxodithioesters in the Copper-Catalyzed Synthesis of Benzo[e]pyrazolo[1,5-c][1,3]thiazine Derivatives
A facile and efficient method for the chemoselective synthesis of benzo [e]pyrazolo [1,5-c] [1,3]thiazine derivatives has been developed by tandem Ullmann Coupling reactions of beta-oxodithioesters (ODEs) with 3-(2-bromoaryl)-1H-pyrazoles in C-S bond formation manner, in which ODEs play dual roles as both a substrate and a ligand. A series of benzo[e]pyrazolo[1,5-c][1,3]thiazine derivatives were provided in good to excellent yields with CuI as the copper source in the presence of NaOH in CH3CN at 80 degrees C Under a N-2 atmosphere.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 20277-69-4. Safety of Sodium methanesulfinate.
Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem