Researchers are common within chemical engineering and are often tasked with creating and developing new chemical techniques, frequently combining other advanced and emerging scientific areas. 82911-69-1, Name is N-(9-Fluorenylmethoxycarbonyloxy)succinimide, belongs to thiazines compound, is a common compound. In a pantent, author is Gomha, Sobhi M., once mentioned the new application about 82911-69-1, Recommanded Product: 82911-69-1.
Synthesis and Characterization of Some New Bis-Pyrazolyl-Thiazoles Incorporating the Thiophene Moiety as Potent Anti-Tumor Agents
A new series of 1,4-bis(1-(5-(aryldiazenyl)thiazol-2-yl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)benzenes 3a-i were synthesized via reaction of 5,5-(1,4-phenylene)bis(3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazole-1-carbothioamide) (1) with hydrazonoyl halides 2a-i. In addition, reaction of 1 with ethyl chloroacetate afforded bis-thiazolone derivative 8 as the end product. Reaction of compound 8 with methyl glyoxalate gave bis-thiazolone derivative 10. The structures of the newly synthesized compounds were established on the basis of spectroscopic evidences and their alternative syntheses. All the synthesized compounds were evaluated for their anti-tumor activities against hepatocellular carcinoma (HepG2) cell lines, and the results revealed promising activities of compounds 3g, 5e, 3e, 10, 5f, 3i, and 3f with IC50 equal 1.37 +/- 0.15, 1.41 +/- 0.17, 1.62 +/- 0.20, 1.86 +/- 0.20, 1.93 +/- 0.08, 2.03 +/- 0.25, and 2.09 +/- 0.19 M, respectively.
Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 82911-69-1, Recommanded Product: 82911-69-1.
Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem