Research speed reading in 2021.The potential utility of systematic synthetic strategy will be applicable to efficient generations of chemical libraries of compounds to find ‘hit’ molecules. 5872-08-2, Name is (7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonic acid, belongs to thiazines compound, is a common compound. In a pantent, author is Hamed, Eman O., once mentioned the new application about 5872-08-2, Application In Synthesis of (7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonic acid.
Cyclization of N-benzyl cyanoacetamide: Novel synthesis and biological activity of pyrrole, pyrimidine, and pyran derivatives
Heteroannulation of N-Benzyl cyanoacetamide 1 to a new series of heterocycles has been developed. Thus, reaction of 1 with different polarized pi systems afforded pyrrolo 4, pyridone 6, pyridine 8, and diazapene 10 derivatives, respectively. N-Benzyl cyanoacetamide that undergo condensation reaction with salicylaldehyde yielded pyran derivative 11. Nitrosation of 11 furnished condensed pyran 13. Compound 11 reacted with benzaldehyde, carbon disulfide (cyclizing agent), and ammonium thiocyanate to provide pyrane 17, thiazine 18, and thiourea 20 derivatives, respectively. Cinnamoyl isothiocyanate was reacted with compound 11 to produce non-isolable thiourea derivative 21. The newly synthesized compounds have been characterized by infrared (IR), proton nuclear magnetic resonance (H-1 NMR), and carbon nuclear magnetic resonance (C-13 NMR) spectral data. The compounds were then evaluated for antibacterial and anticancer activities.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 5872-08-2 is helpful to your research. Application In Synthesis of (7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonic acid.
Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem