Research speed reading in 2021.The potential utility of systematic synthetic strategy will be applicable to efficient generations of chemical libraries of compounds to find ‘hit’ molecules. 7689-03-4, Name is Campathecin, belongs to thiazines compound, is a common compound. In a pantent, author is Haggam, Reda A., once mentioned the new application about 7689-03-4, Safety of Campathecin.
An Efficient Route for Synthesis of a New Class of Quinazolines: Synthesis of Thiazino-, Thiadiazolo-, and Thiazolo- Quinazoline Derivatives
The addition of amino group of anthranilic acid to isothiocyanate 2 provided cinnamoyl thiourea derivative 3. The compound 3 underwent different types of cyclization depending on conditions. The quinazolinthione of type 5 was obtained by treatment with Na2CO3. Quinazolinthione 5 underwent a series of transformation and oxidation reactions to form a new class of quinazoline and thiazoloquinazoline derivatives. All the compounds were tested against antimicrobial and antitumor activity.
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Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem