Research speed reading in 2021. Chemistry is a science major with cience and engineering. The main research directions are chemical synthesis, new energy materials, nano-ceramics,and research on the structure and performance of functional materials. , Recommanded Product: 103-47-9, 103-47-9, Name is N-Cyclohexyltaurine, molecular formula is C8H17NO3S, belongs to thiazines compound. In a document, author is Prasad, Tangella Nagendra, introduce the new discover.
Design, synthesis and biological evaluation of substituted 2-amino-1,3-thiazine derivatives as antituberculosis and anti-cancer agents
A series of substituted 2-amino-1,3-thiazines were synthesized as amides (9a-9i), carbamates (9j-9m), sulfonamides (9n-9o) and urea derivatives (9p-9q) by treating the compound 7 with acid chlorides (8a-8i), chloroformates (8j-8m), sulfonyl chlorides (8n-8o) and isocyanates (8p-8q) respectively. The synthesized compounds (9a-9q) were screened for antituberculosis activity against Mycobacterium tuberculosis H(37)Rv ATCC 27294 and the results show that some of these derivatives possess good activity against Mycobacterium tuberculosis H(37)Rv ATCC 27294. A few also display promising cytotoxic activity against human breast cancer MCF-7 and human esophageal cancer EC-9706 cell lines. Regarding both biological profiles 9b, 9m and 9h are the most active for anti-cancer, anti-TB activity. [GRAPHICS] .
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Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem