Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner.147118-35-2, Name is (R)-Methyl 3-((tert-butyldimethylsilyl)oxy)-5-oxo-6-(triphenylphosphoranylidene)hexanoate, SMILES is O=C(OC)C[C@H](O[Si](C)(C(C)(C)C)C)CC(C=P(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)=O, belongs to thiazines compound. However, they have proven to be challenging because of the mutual inactivation of both catalysts. In a document, author is Mironova, E. V., introduce the new discover, Product Details of 147118-35-2.
Crystal structure of cyclic sulfin- and sulfonamides of the thiazine series: Conformation, intra- and intermolecular interactions
An X-ray crystallographic study of a new compound is performed and the structure of five sulfin- and sulfonamides of the thiazine series is discussed. The conformation of the thiazine ring in all structures (a distorted boat) is stabilized by the intramolecular interaction of the C-HaEuro broken vertical bar N type. The nitrogen atom of the thiazine ring has a pyramidal configuration. The geometry of isolated molecules is calculated at density functional theory level (PBE1PBE, 6-31G(d,p)) and compared to that observed in the crystals. In the crystal structures different packing motifs are implemented with the formation of supramolecular associates of different types due to classical hydrogen bonds such as N-H center dot center dot center dot O.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 147118-35-2. Product Details of 147118-35-2.
Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem