Synthetic Route of 56-17-7. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction by binding to a specific portion of an enzyme preventing a reaction from occurring. Irreversible inhibitors are therefore the equivalent of poisons. 56-17-7, Name is 2,2′-Disulfanediyldiethanamine dihydrochloride, belongs to thiazines compound. Introduce new discover of the category.
Synthesis of a 6-CF3-Substituted 2-Amino-dihydro-1,3-thiazine beta-Secretase Inhibitor by N,N-Diethylaminosulfur Trifluoride-Mediated Chemoselective Cyclization
The synthesis of a 6-CF3-substituted 2-amino-dihydro-1,3-thiazine via N,N-diethylaminosulfur trifluoride (DAST)-mediated cyclization of N-hydroxypropyl thiourea 6 is described. This reaction gave 6-CF3-1,3-thiazine 7 with high chemical yield and chemoselectivity, suppressing the common byproduct of oxazine 8. This new protocol enabled access to 6-CF3-substituted 1,3-thiazine beta-secretase inhibitor 2.
Synthetic Route of 56-17-7, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 56-17-7.
Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem