The prevalence of solvent effects in heterogeneous catalysis in condensed media has motivated developing quantitative kinetic,and theoretical assessments of solvent structures and their interactions with reaction intermediates and transition states. , Application In Synthesis of Campathecin, 7689-03-4, Name is Campathecin, molecular formula is C20H16N2O4, belongs to thiazines compound. In a document, author is Akbarzadeh, Marzieh, introduce the new discover.
Synthesis of novel derivatives of (benz)imidazo[2,1-b]pyrimido[4,5-d][1,3] thiazine
Several derivatives of the novel heterocyclic systems 2-substituted-imidazo- and benzimidazo-[2,1-b)]pyrimido[4,5-d][l,3]thiazine have been synthesised through the one-pot cyclocondensation of 2,4-dichloro-5-(chloromethyl)-6-methylpyrimidine with imidazolidine-2-thione and 1H-benzimidazole-2(3H)-thione and subsequently substituted by various secondary amines in moderately good yields.
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Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem