Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 10297-73-1, Name is 4′-(Methylsulfonyl)acetophenone, molecular formula is C9H10O3S, belongs to thiazines compound, is a common compound. In a patnet, author is Chauhan, Nilesh B., once mentioned the new application about 10297-73-1, HPLC of Formula: C9H10O3S.
Synthesis and biological evaluation of coumarin clubbed thiazines scaffolds as antimicrobial and antioxidant
A new series of 4-methyl-6-nitro-2-oxo-2H-chroman-7yl-2-(4-(4-fluorophenyl)-6-phenyl-2H-1,3-thiazin-2-yl-amino)acetates 5a-j were synthesized from 6-nitro-4-methyl coumarinyl chloroacetate (5) and 2-amino thiazines (IIIa-j). The structure of the final compounds was adequately confirmed via spectroscopic techniques (IR, H-1 NMR, C-13 NMR, Mass) and characterization of physical properties. Final compounds were screened for their antimicrobial, antitubercular, and antioxidant activities. Compounds 5c and 5h found to have antibacterial potency against E. coli with MIC values 50 mu g/mL compared to standard drugs. Compound 5d demonstrated better antifungal potency (MIC = 200 mu g/mL) against C. albicans when compared with griseofulvin. Compounds 5b and 5h found to be encouraging antitubercular (MIC = 62.5 mu g/mL with 98-99% inhibition) against M. tuberculosis H(37)Rv. The newly synthesized 5h and 5b were appeared to have high radical scavenging efficacies as 33.99 +/- 0.301 and 35.35 +/- 0.470 mu g/mL +/- SD of IC50 values, respectively, in DPPH and ABTS bioassay.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 10297-73-1. The above is the message from the blog manager. HPLC of Formula: C9H10O3S.
Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem