38642-74-9, Name is 2-Cyano-phenothiazine, belongs to thiazines compound, Product Details of 38642-74-9, is a common compound. In an article, once mentioned the new application about 38642-74-9.
Identification of a non peptidic RANTES antagonist
A series of phenothiazines demonstrating inhibition of RANTES binding to THP-1 cell membranes has been identified. The lead compound RP23618 (IC50 = 3 muM) was found to inhibit specific binding of 125I-RANTES, but not 125I-MCP-1 to THP-1 cell membranes and furthermore to antagonise RANTES, but not MCP-1-induced chemotaxis of THP-1 cells.
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Reference£º
Thiazine – an overview | ScienceDirect Topics,
Thiazine | C4H5NS – PubChem