Flexible application of 3-Bromo-10H-phenothiazine in synthetic route

According to the analysis of related databases, 3-Bromo-10H-phenothiazine, the application of this compound in the production field has become more and more popular.

An elementary termolecular reaction involves the simultaneous collision of three atoms, 3939-23-9, molecules, or ions. Here is a downstream synthesis route of the compound 3939-23-9, name is :3-Bromo-10H-phenothiazine

2, under the protection of nitrogen will be prepared in step 1 aromatic diamine and phenothiazine derivatives according to 1:1 molar ratio was added to toluene, while adding potassium tert-butyl alcohol and palladium acetate as a catalyst,The reaction was heated to 80 C for 3 hours and then cooled to room temperature. The reaction was filtered,The filtrate was washed with dichloromethane and then the solvent was evaporated to dryness. The crude product was repeatedly washed with methanol and acetone,The product is obtained after purification by column chromatography.

According to the analysis of related databases, 3-Bromo-10H-phenothiazine, the application of this compound in the production field has become more and more popular.

Reference£º
Patent; Changchun Hai Purunsi Technology Co., Ltd.; Guo Jianhua; (12 pag.)CN106831645; (2017); A;,
Thiazine – an overview | ScienceDirect Topics
Thiazine | C4H5NS – PubChem