Rate laws may be derived directly from the chemical equations for elementary reactions. This is not the case, however, for ordinary chemical reactions.1771-18-2, name is :2-Methoxyphenothiazine, below Introduce a new synthetic route.. 1771-18-2
38.1) 2-Methoxy-10H-phenothiazine-1-carbaldehyde: 4.6 g (20 mmol) of 2-methoxy-10H-phenothiazine are dissolved, under an argon atmosphere, in a three-necked flask, containing 140 ml anhydrous ethyl ether. 20 ml (50 mmol) of a solution of nBuLi (2.5 M) in hexane is then added dropwise, at 20 C. The reaction mixture is agitated for 3 hours at 20 C. before the dropwise addition of 6.2 ml (80 mmol) of anhydrous DMF. Agitation is maintained for another 15 hours at 20 C. The whole is then poured into 150 ml ice-cooled water and the product is extracted twice using 200 ml of ethyl acetate. The organic solution is washed with 100 ml of salt water, dried over MgSO4, filtered and concentrated under vacuum. The evaporation residue is taken up in diisopropyl ether, filtered and dried to produce a red solid with a yield of 30%. Melting point: 155-160 C., 1771-18-2
According to the analysis of related databases, 1771-18-2, the application of this compound in the production field has become more and more popular.
Reference£º
Patent; Societe de Conseils de Recherches et d’Applications Scientifiques (S.C.R.A.S.); US6482822; (2002); B1;,
Thiazine – an overview | ScienceDirect Topics
Thiazine | C4H5NS – PubChem