It is a common heterocyclic compound, the thiazines compound, 3,4-Dihydro-2H-benzo[b][1,4]thiazine, cas is 3080-99-7 its synthesis route is as follows.
Example 9: Synthesis of 2- (2, 3-DIHYDROBENZOLL, 4] thiazin-4-ylmethyl)-1, 1, 1-TRIFLUORO-4- (5- fluoro-2-methoxyphenyl)-4-methylpentan-2-ol A solution of 2- [2- (5-fluoro-2-methoxyphenyl)-2-methylpropyl]-2-trifluoromethyloxirane (118 mg) and 3, 4-dihydro-2H-1, 4-benzothiazine (H. I. EL-SUBBAGH et AL., Arch. Pharm. Med. Chem., 1999, 332, pp. 19-24) (122 mg) in dimethylformamide (1 mL) was heated at 140C for 73 hours. The resulting mixture was diluted with diethyl ether, washed with saturated aqueous sodium bicarbonate, water and brine, dried over magnesium sulfate, filtered, and concentrated in vacuo. The residue was purified by radial chromatography with a chromatotron (eluted with 0% to 1% ethyl acetate-hexanes) to give the title compound as a white solid (53.5 mg), m. p. 103C-104C.
3080-99-7, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,3080-99-7 ,3,4-Dihydro-2H-benzo[b][1,4]thiazine, other downstream synthetic routes, hurry up and to see
Reference£º
Patent; BOEHRINGER INGELHEIM PHARMACEUTICALS, INC.; WO2004/63163; (2004); A1;,
Thiazine – an overview | ScienceDirect Topics
Thiazine | C4H5NS – PubChem