As a common heterocyclic compound, it belongs to thiazines compound, name is 3-Oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylic acid, and cas is 272437-84-0, its synthesis route is as follows.
Acid (4a) in tetrahydrofuran (SOmL) and triethylamine (4.7mL) was cooled to 0C and isobutylchloroformate (4.02mL) was added dropwise and the solution was stirred at 0C for 2 hours, when it was filtered into a stirred solution of sodium borohydride (3. 14g) in ice/water (50mL). The mixture was stirred at 0C for 1 hour and allowed to warm to room temperature. It was acidified with 2M hydrochloric acid, evaporated to half volume, and the resulting product was collected, washed with water and dried in vacuo, to give a white solid (4. 5g). MS (-ve ion electrospray) m/z 194 (M-H)-
272437-84-0, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,272437-84-0 ,3-Oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylic acid, other downstream synthetic routes, hurry up and to see
Reference£º
Patent; SMITHKLINE BEECHAM P.L.C.; WO2003/87098; (2003); A1;,
Thiazine – an overview | ScienceDirect Topics
Thiazine | C4H5NS – PubChem