As a common heterocyclic compound, it belongs to thiazines compound, name is 3-Bromo-10H-phenothiazine, and cas is 3939-23-9, its synthesis route is as follows.
Compound 1 was synthesized by the modification of the published method [18]. Sodium hydride(2.2 g, 53.9 mmol) was stirred with 3-bromo-10H-phenothiazine (10.0 g, 35.9 mmol, dissolved in dryDMF) for 30 min. Bromoethane (4.7 g, 43.1 mmol) was then added to the mixture and stirred for 10 hat room temperature in dark environment. After the reaction completed, water was added to react theremaining sodium hydride. White solid was precipitated and collected by vacuum filtration. The solidwas first washed with small amount of EA and then washed with n-hexane. 1H NMR (400 MHz,acetone-d6) 7.34 (dd, J = 8.7, 2.3 Hz, 1H), 7.28 (d, J = 2.3 Hz, 1H), 7.25-7.19 (m, 1H), 7.15 (dd, J = 7.6,1.5 Hz, 1H), 7.04 (dd, J = 8.3, 1.2 Hz, 1H), 6.99 (d, J = 1.2 Hz, 0H), 6.97 (s, 1H), 6.95 (s, 1H), 3.99 (q,J = 6.9 Hz, 2H), 1.38 (t, J = 6.9 Hz, 3H).
3939-23-9, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,3939-23-9 ,3-Bromo-10H-phenothiazine, other downstream synthetic routes, hurry up and to see
Reference£º
Article; Lao, Hio Kuan; Tan, Jingyun; Wang, Chunfei; Zhang, Xuanjun; Molecules; vol. 24; 19; (2019);,
Thiazine – an overview | ScienceDirect Topics
Thiazine | C4H5NS – PubChem